Cancer Biology
Concepts with 100%
correct answers
what kind of disease is cancer?
genetic
what does cancer stem from?
dysregulation of cell/tissue growth
what is cancer due to?
acquisition of somatic mutations in genes that normally
control cell proliferation, differentiation, DNA maintenance
& repair, apoptosis (programmed cell death), adhesion,
and angiogenesis
how long does it take to transform a normal cell to an
invasive/ metastatic cancer?
at least 6-8 mutations over many years in various genes
regulating these processes
individual tumors usually have what within them?
significant genetic heterogeneity
is cancer hereditary?
Cancers usually stem from somatic mutation events but
can be hereditary in rare cases
benign tumor
tumor remains confined to original location and is
amenable to surgery
, malignant tumor
invades surrounding tissue, spreads throughout body via
direct seeding, hematogenous system or lymphatic system
(metastasis)>>> CANCER
benign tumor:
growth pattern
rate of growth
differentiation
metastasis
expansive
typical
hyperplasia
proliferation of cells within an organ or tissue. It can
result in the gross enlargement of an organ or in a benign
tumor
metaplasia
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