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Nagelhout 6 Exam Study Guide.
Ionized drugs
nonionized drugs - Answers✔________ drugs are soluble in H2O and therefore are not
absorbed via the stomach, cross the blood-brain barrier, and placenta, whereas, ________ are
lipophilic and can penetrate these barriers.
pKa (dissociation constant) - Answers✔the degree of ionization at a particular site is
determined by the ____________ and the pH gradient across the membrane.
acids - Answers✔proton donors are considered ________, whereas proton acceptors are called
_________.
gastric juice
duodenum
ileum
large intestine
plasma
CSF
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