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Genetics Chapter 18 Genomics, Bioinformatics, and Proteomics questions and answers
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Genetics Chapter 18 Genomics, Bioinformatics, and Proteomics questions and answers
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Genetics: Chapter 18:Genomics,
Bioinformatics, and
Proteomics questions
and answers
what is the genome? - answer the genome is the
complete set of DNA in a single cell of an organism
genomics - answer the study of genomes; it allows
the sequencing of entire genomes
genomes encompasses: - answer -structural
genomics: (historical meaning: genome
sequencing)
-functional genomics
-comparative genomics
-metagenomics
structural genomics - answer focuses on
sequencing genomes and analyzing nucleotide
sequences to identify genes and other important
sequences such as gene-regulatory elements
, the most widely used strategy for sequencing and
assembling an entire genomes involves variation of
what method - answer whole-genome shotgun
sequencing
what is whole-genome shotgun sequencing -
answer -the entire chromosome is cut into short,
overlapping fragments using restriction enzymes
-the overlapping fragments are adjoining segments
that collectively form one continuous DNA
molecule within a chromosome called a contig
contigs/contiguous fragments - answer continuous
DNA fragments; overlapping fragments that are
adjoined segments collectively to form one
continuous DNA molecule
DNA sequence alignment - answer in which similar
sequences of bases, such as contains, are lined up
for comparison; one of the earliest bioinformatics
applications to be developed
computer-automated DNA sequencing instruments
can process - answer millions of base pairs per day
with greater efficiency and reduced cost
-designed for high-throughput sequencing
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