,Chapter01:DrugRegulation,Actions,andResponses,f ,f il ,f ,f
Workman&LaCharity:UnderstandingPharmacology:EssentialsforMedicationSafety,3ndEdition
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MULTIPLE CHOICE ,f
,f BASICCONCEPT
S
1. Whichhealthcareprofessionalhasthemajorresponsibilityfordispensingpre ,f ,f ,f ,f ,f ,f ,f ,f ,f
scribeddrugsunderthedirection ofapharmacist? ,f ,f ,f ,f ,f ,f
a. Physician
b Nursepractitioner
.
c. Licensednurse ,f
d Pharmacy technician il
.
ANS: D , f
Thephysicianandnursepractitionerhavethemajorresponsibilityforprescribingdrugs,notdispe
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nsingthem.Thelicensednursehastheprimaryresponsibilityforadministeringdrugs,althoughu
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ndersomecircumstancesalicensednursemaydispenseprescribeddrugsbutthis
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isnothisorhermajorresponsibilityindrugtherapy.Thepharmacytechnicianhasthemajorrespon
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sibilityofdispensingprescribeddrugsunderthedirectionofalicensedpharmacist.
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DIF: CognitiveLevel:Remembering ,f ,f REF: p.3 ,f
2. Whichtermdescribestheeffectofadrugthatimprovesbodyfunction? ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f
a. Sideeffect
b Intended action il
.
c. Adversereaction
d Idiosyncraticresponse ,f
.
ANS: B , f
The purpose of drug therapy is to take a drug to prevent, reduce, or correct a health
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problem.Thisresponseisanydrug’sintendedactionalsoknownasatherapeuticresponse.
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DIF: CognitiveLevel:Remembering ,f ,f REF: p.3 ,f
3. Whicht ypeofdrugname is―owned‖b ythecompanythatmanufacturesit? ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f
a. Genericname ,f
b Chemicalname
, .
c. Categoryname
d Trade name il
.
ANS: D , f
The chemical name is a drug’s exact chemical composition. The generic name is the name
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assigned to the drug by the U.S. Adopted Names Council and is not owned by anyone. The
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category name refers to the type of drug (what it does or what it is used for) and is not an
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actualdrugname.Thetradename(brandname)isthenameprovidedandownedbyaspecificdrug’s
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manufacturer.
DIF: CognitiveLevel:Remembering ,f ,f REF: p.4 ,f
4. Which drug or drug class is a ―high alert‖ drug? il il il il il il il il il
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS: B , f
A high alert drug is one in which harm is likely to result if given at the wrong dose, to the wrongpatient,
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or not given to the correct patient. Drugs classified as high alert drugs include
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potassium,narcotics(opioids),insulin,cancer chemotherapydrugs, andheparin(oranydrugthatstrongly
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affects blood clotting). Penicillin, NSAIDs, and calcium are not considered high alert drugs.
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DIF: CognitiveLevel:Remembering ,f ,f REF: p.4 ,f
5. Whatisthetermforadrugthathasthesameactionasanaturallyoccurringbodyh ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f
ormoneorenzyme? ,f ,f
a. Agonist
b Blockingagent ,f
.
c. Chemical
d Duplicator
.
ANS: A , f
Adrugagonistisanextrinsicdrugthatactivatesthereceptorsitesofacellandmimics
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theactionsofnaturallyoccurring bodysubstances (intrinsic drugs).Ablocking agent is adrug
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, antagonist.Achemicalwouldnotnecessarilybeadrugatall.Aduplicatorisnota ,f ,f ,f ,f ,f ,f ,f ,f il ,f ,f ,f
pharmacologicterm.
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DIF: CognitiveLevel:Remembering ,f ,f REF: pp.6-7 ,f
6. Whichtermdescribeshowthebodyaffectsdrugactivity? ,f ,f ,f ,f ,f ,f ,f
a. Drugpotency ,f
b Pharmacodynamics
.
c. Therapeuticeffect
d Pharmacokinetics
.
ANS: D , f
The term pharmacokinetics refers to drug metabolism and how the body changes a drug.
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Pharmacodynamicsreferstohowadrugworkstochangebodyfunction.Drugpotencyreferstohowstro
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nglyortowhatdegreeadrugexertsitseffects.Thetherapeuticeffectiscloserto
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pharmacodynamics,meaninghowadrugworkstochangebodyfunction.
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DIF: CognitiveLevel:Remembering ,f ,f REF: p.10 ,f
7. IntheUnitedStates,whichgroupisresponsibleforenforcingestablished
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standardsfordrugmanufacturing?
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a. U.S.Pharmacopeia ,f
b NationalInstitutesofHealth ,f ,f ,f
.
c. Food and Drug Administration il il il
d AssociationofPharmaceuticalManufacturers ,f ,f ,f
.
ANS: C , f
The standards for drug manufacture are established by the U.S. Pharmacopeia. These standards are
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enforced by the Food and Drug Administration. Neither the National Institutes of Health
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northeAssociationofPharmaceuticalManufacturers hasanyauthorityto enforcedrugstandards.
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DIF: , f , f CognitiveLevel:Remembering ,f ,f ,f ,f ,f ,f ,f , f REF: p.5 ,f ,f ,f ,f ,f
8. Which factor is a major disadvantage of the transdermal drug delivery route? il il il il il il il il il il il
a. Onlyaprescribercan administerdrugsbythetransdermal route.,f ,f ,f ,f ,f ,f ,f
b Transdermaldrugsmustbesterileratherthanclean. ,f ,f ,f ,f ,f ,f ,f
.
c. Firstpassdruglossbythisrouteisthemostextensive.
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d Drug absorption is dependent on adequate circulation.
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