NURS 5334 - MODULE 5 QUESTIONS AND
ANSWERS LATEST UPDATED 2025
LoopZDiureticsZ-ZcorrectZanswer-FurosemideZ(Lasix),Zethacyrnic,Zbumetanide,Ztorsemide
MOA:ZworkZinZascendingZloopZofZhenleZtoZblockZsodiumZandZchlorideZreabsorption
allZmayZcause:Zototoxicity,Zhypovolemia,Zhypotension,Zhypokalemia,Zhyperuricemia,Zhyperglycemia,ZandZ
disruptionZofZlipidZmetabolism
ex:ZifZpatientZhasZgout,ZquestionZifZlasixZappropriate.ZbutZifZpatientZhasZchf,ZmightZnotZhaveZaZchoice
ThiazideZdiureticsZ-ZcorrectZanswer-sulfaZdiureticsZ(soZcanZhaveZcrossZallergyZtoZabx)Z
-Zhctz,Zmetolazone,ZChlorthalidoneZ
-ZMOA:ZincreaseZtheZrenalZexcretionZofZsodium,Zchloride,ZpotassiumZandZwaterZ
-ZworkZinZdistalZconvolutedZtubuleZ
txZuse:Zhtn,Zedema,ZdiabetesZinsipidus
osmoticZdiureticZ-ZcorrectZanswer-mannitolZ
reducesZICP,ZgivenZparenterally
PotassiumZsparingZdiureticsZ-ZcorrectZanswer-AldosteroneZantagonistsZ-
>ZspironolactoneZ(bbZtumorgenicZinZrats)ZandZesplerenoneZ
txZuse:Zhtn,Zchf,Zhirsutism,Zacne,ZpcosZ(blocksZandrogenZreceptorsZ
ex:ZifZpatientZhasZbpZthatZisZnotZcontrolledZandZonZ3/4ZdiffZmeds,ZthisZisZgoodZclassZtoZtry
decreaseZmorbidityZandZmortalityZinZchfZpatientsZ
non-aldosteroneZantagonistsZ->Ztriameterene,Zamiloride
ACEZinhibitorsZ-ZcorrectZanswer-
txZuse:Zhtn,Zchf,Zmi,ZdiabeticZandZnondiabeticZnephropathy,ZpreventionZofZmi,ZstrokZandZdeathZinZptsZatZhig
hZcvZriskZ
, s/e:ZfetalZinjuryZ(don'tZgiveZtoZpeopleZofZchildZbearingZageZunlessZonZbirthZcontrol),ZfirstZdoseZhypotension,
ZcoughZ(accumulationZofZbradykinin)Zangioedema,Zhyperkalemia,Zneutropenia,ZrenalZfailureZ(kidneyZprote
ctiveZtoZaZcertainZpoint,ZbutZifZatZendZstagesZcanZgetZtoZrenalZfailure)Z
**ifZgivenZwithZlasixZcanZcounteractZtheZhyperkalemiaZ
**allZdiabeticsZshouldZbeZonZanZACEZinhibitorZorZARBZbecauseZitZprotectsZthemZfromZnephropathy
ARBZ-ZcorrectZanswer-AngiotensinZIIZReceptorZBlocker
txZuse:Zhtn,Zchf,Zmi,ZdiabeticZandZnondiabeticZnephropathy,ZpreventionZofZmi,ZstrokZandZdeathZinZptsZatZhig
hZcvZriskZ
s/e:ZfetalZinjuryZ(don'tZgiveZtoZpeopleZofZchildZbearingZageZunlessZonZbirthZcontrol),ZfirstZdoseZhypotension,
Zangioedema,Zhyperkalemia,Zneutropenia,ZrenalZfailureZ(kidneyZprotectiveZtoZaZcertainZpoint,ZbutZifZatZendZs
tagesZcanZgetZtoZrenalZfailure)Z
sameZsideZeffectsZasZaceZinhibitorsZwithZlessZriskZofZcoughZbecauseZtheyZdoZnotZpromoteZaccumulationZofZ
bradykininZinZtheZlung
directZreninZinhibitorZ-ZcorrectZanswer-aliskirenZ
notZprescribedZaZlotZ
butZisZanZoptionZ
sameZs/eZasZarbsZandZaces
calciumZchannelZblockersZ-ZcorrectZanswer-decreaseZcalciumZinsideZtheZcellZandZcauseZvasodilation
dihydropyridinesZ-ZcorrectZanswer-nifedipine,Zamlodipine,Zfelodipine,ZnicardipineZ
txZuse:Zangina,Zhtn,Zmigraines,Zinvestigational:ZsuppressZpretermZlaborZ