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RADIOLOGIC TECHNOLOGY BASICS AND FUNDAMENTALS

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Radiologic Technology Basics and Fundamentals is a comprehensive guide designed for students, professionals, and anyone interested in the field of radiologic technology. This document provides a clear and concise overview of the foundational principles, techniques, and equipment used in diagnostic ...

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  • December 23, 2024
  • 43
  • 2024/2025
  • Class notes
  • Bushong
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kezielmaranion265
C1 RADIOBIOLOGY
Study of effects of ionizing radiation in biologic tissue


HUMAN RADIATION RESPONSE
Increases with severity with increasing
radiation dose

DETERMINISTIC EFFECT
SEVERITY
NON- STOCHASTIC EFFECT
OCCURENCE:


DAYS POST EXPOSURE

Incidence of radiation response increases
with increasing radiation dose

PROBABILISTIC EFFECT INCIDENCE

STOCHASTIC EFFECT
OCCURENCE:


OBSERVES FOR MONTHS/ YEARS



Biologic Interaction
Atom/ atomic level determines the radiation interaction

85%



C1 RADIOBIOLOGY 1

, Hydrogen

Oxygen

Molecular/ tissue level determines the radiation response


Cellular Theory

ROBERT HOOK


1665
History/ People


CELL
- building block

SCHENEIDER & SCHWANN
ANTON VAN LEEUWENHOOK
1838
1973
PLANTS AND ANIMAL
MICROSCOPIC OBSERVATION OF CELL
CELL AS BASIC FUNCTIONAL UNITS

WATSONS & CRICK


1953


MOLECULAR STRUCTURE OF DNA


GENOME MAPPING




MOLECULAR COMPOSITION
NUCLEIC ACID a type of macromolecule WATER
that contains DNA
- DELIVERS ENERGY
that is most critical and the most - ABUNDANT IN THE BODY
radiosensitive target molecules - CONTRIBUTES TO RADIATION EFFECTS



80%




C1 RADIOBIOLOGY 2

, H20


FREE STATE + BOUND STATE



FXN:


maintains body temperature


biochemical reactions
PROTEINS


15%


long chain of macromolecule


Chain: AMINO ACIDS


MACROMOLECULES connected by PEPTIDE BONE


1. PROTEINS NUMBER: 22
2. LIPIDS
3. NUCLEIC ACIDS FXN:
4. CARBOHYDRATES
- PROTEIN SYNTHESIS


- STRUCTURE AND SUPPORT (MUSCLES)



- ENZYMES HORMONES


- ANTIBODIES

Metabolism LIPIDS



1. Catabolism: breaking down of COMPOSED OF:
macromolecules into smaller units
1. HYDROGEN
2. Anabolism: production of 2. OXYGEN
macromolecules 3. CARBPN


(HOC)


2 TYPES




C1 RADIOBIOLOGY 3

, 1. GLYRCEROL (1 in each molecule)


2. FATTY ACID (3 in each molecule)


LIPIDS FUNCTION
- present in all tissues of the body
- under the skin: Thermal insulator
- fuel: stores energy
CARBOHYDRATES


COMPOSED OF:


1. HYDROGEN
2. OXYGEN
3. CARBON


(similar to lipids)


ALSO CALLED AS
SACCHARIDES
ENZYMES
- biochemical reaction
ALSO KNOWN AS SUGARS


2 TYPES:


1. MONOSACCHARIDES


2. DISSACHARIDES


CARBOHYDRATES FUNCTION
- provides fuel in the body
by: GLUCOSE
- provide shap and stability

HORMONES NUCLEIC ACIDS
- exercise regulatory control
2 PRINCIPAL COMPONENT
secretes by
ENDOCRINE GLANDS 1. RNA
- transfer RNA (tRNA)
- pituitary - messenger RNA (mRNA)
- adrenal -
- thyroid FUNCTION: PROTEIN SYNTHESIS




C1 RADIOBIOLOGY 4

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