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Quantitative Article Critique

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This journal article explores the efficacy and safety of metformin as an adjunct to insulin in treating overweight adolescents with type 1 diabetes. The authors cite the inconclusive nature of previous studies addressing the same subject and highlight the need for evidence-based supportive inferenc...

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  • December 26, 2024
  • 2
  • 2024/2025
  • Essay
  • Unknown
  • A+

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Quantitative Article Critique 2

Libman, I. M., Miller, K. M., DiMeglio, L. A., Bethin, K. E., Katz, M. L., Shah, A., Simmons, J.

H., Haller, M. J., Raman, S., Tamborlane, W. V., Coffey, J. K., Saenz, A. M., Beck, R.

W., & Nadeau, K. J. (2015). Effect of metformin added to insulin on glycemic control

among overweight/Obese adolescents with type 1 diabetes. JAMA, 314(21), 2241.

https://doi.org/10.1001/jama.2015.16174

This journal article explores the efficacy and safety of metformin as an adjunct to insulin

in treating overweight adolescents with type 1 diabetes. The authors cite the inconclusive nature

of previous studies addressing the same subject and highlight the need for evidence-based

supportive inferences to necessitate using metformin in pharmacotherapy addressing obesity and

diabetes. Indeed, some pharmacological studies are inconclusive and shallow, hindering efficacy

in treating different infections with certainty. The correlation between diabetes and obesity

requires in-depth and specific research to highlight gaps in practice and knowledge and help in

this critical infections management. The research adopts a quantitative research design because

attaining the research purpose requires measurements, statistical analysis, and computations to

generate informative figures and statistics. Besides setting the exclusion criteria to guide the

purposive sampling approach, the authors ensure that the participants uphold racial and gender

inclusivity, implying the generalizability of research findings and inferences. Random sampling

determines the participants' reliance on placebo or the metformin dosage within the

experimentation period, building research validity and reliability. Measurements are made

before, throughout, and after the intervention to assess the weight loss among the patients, with

the collated data serving as input in statistical models to derive findings in figures and statistics.

The results imply that adding metformin did not improve glycemic control over the stipulated

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