USMLE Step 1 Rapid Review Exam ||
Questions & Answers (Rated A+)
Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints - ANSWER -
Marfan's (fibrillin defect)
Athlete with polycythemia - ANSWER - Erythropoietin injection
Abdominal pain, ascites, hepatomegaly, (also high D dimer, CHF without JVD) -
ANSWER - Budd-Chiari syndrome
Achilles tendon xanthoma - ANSWER - Familial hypercholesterolemia
Adrenal hemorrhage, hypotension, DIC - ANSWER - Waterhouse-Friderichsen
syndrome (meningococcemia)
Back pain, fever, night sweats, weight loss - ANSWER - Pott's (TB to the vertebrae)
Bilateral hilar adenopathy, uveitis - ANSWER - Sarcoid
Blue sclera - ANSWER - Osteogenesis imperfecta
Bluish line on gingiva - ANSWER - Burton's line - lead poisoning
Bone pain, bone enlargement, arthritis, (also increased hat size, fracture, increased alk
phos) - ANSWER - Paget's
Bounding pulses, diastolic hear murmur, head bobbing - ANSWER - Aortic regurg
Child with fever develops red rash on face that spreads to body - ANSWER - Slapped
cheek - B19
Chorea, dementia, caudate degeneration - ANSWER - Huntington's
Chronic exercise intolerance with myalgia, fatigue, painful cramps - ANSWER -
McArdle's (muscle phosphorylase deficiency)
Cold intolerance - ANSWER - Hypothyroidism
Conjugate lateral gaze palsy, horizontal diplopia - ANSWER - Internuclear
ophthalmoplegia (MS or stroke)
Continuous machinery heart murmur - ANSWER - PDA
, Cutaneous/dermal edema due to CT expansion - ANSWER – Myxedema
Café-au-lait spots, Lisch nodules - ANSWER - NF (1 = optic glimoas and pheo, 2 =
acoustic Schwannomas)
Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty - ANSWER -
McCune-Albright syndome (G protein problem)
Calf pseudohypertrophy - ANSWER - Duchenne's muscular dystrophy
Cherry-red spot on macula - ANSWER - Tay-Sachs, Niemann-Pick, central retinal artery
occlusion
Chest pain, pericardial effusion/friction rub, persistent fever following MI - ANSWER -
Dressler's (autoimmune post-MI)
Child uses arms to stand up from squat - ANSWER - Gower's sign (Duchenne's)
Dark purple skin / mouth nodules - ANSWER - Kaposi's sarcoma
Deep, labored breathing / hyperventilation - ANSWER - Kussmaul breathing, DKA
Dermatitis, dementia, diarrhea - ANSWER - Pellagra (B3 / niacin deficiency)
Dilated cardiomyopathy, edema, polyneuropathy - ANSWER - Wet beriberi (B1 /
thiamine deficiency)
Dog or cat bite resulting in infection - ANSWER - Pasteurella multocida (local cellulitis)
Dry eyes, dry mouth, arthritis - ANSWER - Sjogren's syndrome
Dysphagia (esophageal webs), glossitis (smooth tongue), iron deficiency anemia -
ANSWER - Plummer-Vinson syndrome
Elastic skin, hypermobility of joints - ANSWER - Ehler-Danlos (type III collagen)
Enlarged. hard left supraclavicular node - ANSWER - VIrchow's node (abdominal met)
Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells - ANSWER -
Sezary syndrome (cutaneous T cell lymphoma)
Facial muscle spasm upon tapping - ANSWER - Chvostek's sign (hypocalcemia)
Fat, female, fertile, forty - ANSWER - Gallstones
