Pharm List of Exam Drugs:
Upper Respiratory Drugs
Antihistamines:
1st generation antihistamines:
o Diphenhydramine
Indication/Use Action Side Effect Nursing
Considerations/
Contraindications
Treat acute and Competes with Drowsy, dry mouth, Avoid
allergic rhinitis, histamine 4 receptors dizzy, blurred vision, operating
prevent/treat sites- prevents wheezing, motor
anaphylaxis, motion histamine response photosensitivity, UR, vehicles if
sickness Reduces constipation drowsiness
nasopharyngeal occurs
secretions, itching, Avoid alcohol
sneezing and other
CNS
depressants
Use sugarless
candy or gum,
as well as ice
chips for
temporary
relief of
mouth
dryness
Assess
congestion,
lung sounds,
and
characteristics
of secretions
CONTRA:
Severe liver
disease,
narrow-angle
glaucoma, UR
2nd Generation antihistamines= NON-sedating antihistamines (Less sedation and
anticholinergic effects)
o Cetirizine
o Fexofenadine
o Loratadine
,Nasal Decongestants:
Oxymetazoline
Naphazoline
Pseudoephedrine
Indication/Use Action Side Effect Nursing
Considerations/
Contraindications
Nasal congestion Stimulate alpha Nervous, jittery, Frequent use=
adrenergic receptors: restless, HTN tolerance and
Produces nasal rebound
vasoconstriction, congestion,
shrinks mucous DO NOT
membranes, reduce USE
secretions LONGER
THAN 5
DAYS!!
Assess
congestion,
lung sounds,
and
characteristics
of secretion
Intranasal Glucocorticoids:
Fluticasone
Triamcinolone
Indication/Use Action Side Effect Nursing
Considerations/
Contraindications
Allergic Rhinitis Anti- HA, fatigue, restless, Take as
inflammatory/immun insomnia, rebound directed
e modifier congestion, Do not
anticholinergic overuse-
symptoms, rebound
hypersensitivity congestion
reaction Use
Bronchodilato
r first!!!
Expectorants:
Guaifenesin
,Indication/Use Action Side Effect Nursing
Considerations/
Contraindications
Allergy, cold, cough Loosen bronchial Drowsiness, N,V,D, Assess lung
treatment secretion Hypersensitivity sounds n
reaction secretions
(amount/color
)
Antitussives:
Guaifenesin
Codeine
Benzonatate
Indication/Use Action Side Effect Nursing
Considerations/
Contraindications
Manage mild to Bind to opiate Sedation, Vitals (bp, p,
moderate pain, severe receptors, suppress hypotension, rr)
cold/cough cough reflex bradycardia, Assess bowel
NON- respiratory function
PRODUCTIVE, depression, N, V, D Assess
IRRITATING cough/lung
COUGH sounds
Lower Respiratory Drugs
“BAM” Team-Bronchodilators:
Beta 2 Agonist:
o Isoproterenol
o Metaproterenol
o Albuterol- “rescue inhaler”
Indication/Use Action Side Effect Nursing
Considerations/
Contraindications
Treat bronchospasm Binds to beta 2 Nervous, tremors, Monitor pt for
in chronic asthma or receptors, relax restless, flushing, worsening
COPD smooth muscle of HA, N, V, respiratory
bronchi tachycardia, symptoms
palpitations, HTN, Monitor HR
fluid/electrolyte and BP
imbalances
, Anticholinergic:
o Ipratropium
Indication/Use Action Side Effect Nursing
Considerations/
Contraindications
Maintenance of Dilates bronchioles Dizzy, HA, nervous Caution:
COPD Narrow-angle
glaucoma
Teach pt how
to use inhaler
**RINSE
mouth after
using inhaler
Methylxanthines:
o Theophylline
Indication/Use Action Side Effect Nursing
Considerations/
Contraindications
Maintenance therapy Relax smooth Dysrhythmias, NARROW.
of chronic stable muscle nervous, irritability, THERAPEUTI
asthma insomnia, dizzy, C INDEX!!
flushing, dizzy, Contra: seizure,
hypotension, cardiac, renal, or
seizure, gi distress, liver disorders
intestinal bleeding,
hyperglycemia,
tachycardia,
palpitations, cardio
respiratory collapse
“SLM” Team-Anti-inflammatories:
Corticoid Steroids:
o Methylprednisolone
o Fluticasone: inhaler
o Triamcinolone: tablet
o Dexamethasone: injection
Leukotriene receptor antagonist:
o Montellukast
o Zafirlukast
Indication/Use Action Side Effect Nursing
Considerations/
Contraindications
PROPHYLACTIC Reduce inflammatory Dizzy, HA, GI Assess lung