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UNE Medical Biochemistry Midterm Exam Questions and Answers 100% Pass | Reviewed

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  • UNE Biochemistry

UNE Medical Biochemistry Midterm Exam Questions and Answers 100% Pass | Reviewed Which of the following proteins is likely to have quaternary structure? - A multimeric protein that contains multiple peptide chains Prosthetic groups are complex nonprotein molecules that participate in catalysis...

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  • January 8, 2025
  • 10
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • UNE Biochemistry
  • UNE Biochemistry
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EmilyCharlene
UNE Medical Biochemistry
Midterm Exam Questions and
Answers 100% Pass | Reviewed

Which of the following proteins is likely to have quaternary structure? - ✔✔A multimeric protein that

contains multiple peptide chains


Prosthetic groups are complex nonprotein molecules that participate in catalysis by providing functional

groups that form a covalent intermediate between the enzyme and the substrate. Which of the following

is an example of a coenzyme or cofactor that participates in a covalent catalysis reaction? - ✔✔Pyridoxal

phosphate


Which of the following best describes a protein domain? - ✔✔A section of a protein structure sufficient to

perform a particular chemical or physical task


Cleavage of fructose 1,6 bisphosphate to dihydroxyacetone and Glyceraldehyde 3-phosphate involves the

breaking of a carbon-carbon bond through a process other than oxidation or hydrolysis. This is achieved

by what class of enzymes? - ✔✔Lyase


A 55-year old man is brought to the emergency room with a chief complaint of chest pain and tingling in

his left arm. Elevation of which of the following enzymes in circulation would be most indicative of

myocardial infarction? - ✔✔Troponin


Allosteric activators of hemoglobin will increase substrate binding through which of the following

mechanisms? - ✔✔Binding the protein, and keeping it in the "R" conformation




EMILY CHARLENE © 2025, ALL RIGHTS RESERVED 1

, Which of the following best describes tertiary structure? - ✔✔Interactions between alpha helices and beta

sheets to form a domain


How do most enzymes reduce the activation energy needed to move a reaction forward? - ✔✔providing

an active site most complementary to the transition state


Domains are common structural elements that retain a particular function within the protein. Which of

the following is an example of a protein domain? - ✔✔An arrangement of beta-strands connected by

alpha-helices (beta-alpha-beta-alpha)


Which amino acid would not be commonly found in the middle of an alpha-helical domain? - ✔✔Proline


Which of the following is a true statement with regards to the malate-aspartate shuttle system? -

✔✔Generates 2.5 molecules of ATP in mitochondria per each NADH from glycolysis.


Complex II (Succinate Q-reductase) is not considered part of the process of oxidative phosphorylation

because it is unable to do which of the following activities? - ✔✔Pump protons from the mitochondrial

matrix into the inter membrane space.


Succinate is a substrate for which complex in the electron transport chain? - ✔✔Complex II (Succinate-Q

reductase)


The glycerophosphate shuttle is the major shuttle of most tissues. Which of the following best describes

the transfer of electrons by this shuttle? - ✔✔Electrons are directly transferred from glycerol 3-phosphate

to an FAD containing glycerol phosphate dehydrogenase.


A 19-year old male is being evaluated for muscle weakness. Evaluation of a muscle biopsy revealed

normal rates of succinate oxidation but very low rates of pyruvate oxidation. Further testing determined

normal levels of enzymatic activity in both malate dehydrogenase and pyruvate dehydrogenase. Based

on this data, the patient may have a mutation in a gene encoding for which mitochondrial protein? -

✔✔Complex I (NADH Q-oxidoreductase)




EMILY CHARLENE © 2025, ALL RIGHTS RESERVED 2

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