PCB 4233 Immunology Exam 1
2025
,PCB 4233 Immunology Exam 1 questions and answers
PCB 4233 Immunology Exam 1
questions and answers
immune system 4 functions - -distinguish between self and altered self
-distinguish between self and foreign invaders
-promote mutualistic microorganism interactions
-distinguish between foreign pathogens
fluMIST - attentuated virus
-not good for immunocompromised people
intramuscular influenza vaccination - inactivated virus
Dr. Ron Fouchier - used ferrets as model to test mechanisms regulating
infectivity/pathogenicity - how to build a better influenza
-restricted from publish - bioterrorism
Hemagglutinin - One of the enzymes found on the surface of the Influenza virus;
allows virus to fuse into the cell it is infecting
Neuraminidase - One of the enzymes found on the surface of the Influenza virus;
allows virus to exit infected cell which promotes the release of progeny viruses
from infected cells (infectivity)
PCB 4233 Immunology Exam 1 questions and answers
, PCB 4233 Immunology Exam 1 questions and answers
Thucydides - 430 BC noted that those who had recovered from plague could nurse
the sick without repeat contraction of disease; first to come up with idea of
immunis, meaning exempt
variolation - an early method of vaccination using infected material from a patient
-15th century Turks and Chinese took dried crusts from smallpox pustules and
inhaled/inserted into cuts of skin
Ed Jenner - 1798 - noted that milk maids who developed cowpox (milder disease)
were immune to smallpox
-inoculated 8 y/o with cowpox and infected with smallpox
Pustules - contain puss, immune cell, and attenuated virus -- resembles virus
Smallpox - A highly contagious viral disease characterized by fluid filled blisters
on skin, scarring, blindness, and limb deformities
-humans are the reservoir for the virus (unique to humans)
-completely eradicated (vaccination is stronger than virus encountered in nature)
-Variola major (30% death) or Variola minor (1%)
attenuated vaccine - vaccine composed of a weakened form of the pathogen that is
generally unable to cause disease
-Louis Pasteur
mumps - contagious viral disease that leads to painful swelling of the salivary
glands
PCB 4233 Immunology Exam 1 questions and answers