What is the hypothesized role of adipose tissue in fatty liver disease?
visceral fat releases signals that disrupt how the body handles glucose and fat leading to more fat being stored in the liver
Excess fat in liver causes liver distress
Why does liver damage occur from the hypothesized role...
NSG 533 EXAM 2 MODULE 5
Hepatitis A: What to obtain for patient history
history of blood transfusion
msm
poor sanitation
travel to developing nations (contaminated food or water!)
exposure to an infected person
family history
True / False most cases of Hep A are symptomatic
TRUE
What cases of hep a are not symptomatic?
children under 6 years old (70% are symptomatic)
What are some clinical presentations for Hep A?
flu-like symptoms
fever
fatigue
loss of appetite
N/V/D
abd pain
dark urine
CLAY COLORED STOOLS
joint pain
,jaundice: cholestasis, hyperbilirubinemia
--Decreased albumin and prolonged PT--
Hepatitis B: What to obtain for patient history
75% positive cases in Asia
Hemodialysis
Multiple blood transfusions (esp internationally)
use of immunosuppressive drugs
Perinatal - HEP B status of pregnant mothers
multiple sex partners
household infection of HBV
occupational exposure
IVDU
Nosocomial
Is Hep B acute or chronic?
BOTH! Can be acute or chronic
What to look for (history) in acute Hep b infection?
exposure with infected blood or fluid within the past few months
What to look for (history) in chronic Hep B infection?
history of risk factors, serologic testing (+) for 6 months
Clinical Presentations of ACUTE Hep B
, FLU LIKE SYMPTOMS
general illness
anorexia
N/V
body aches
mild fever
dark urine
jaundice
Clinical presentations for chronic Hep B
CAN BE ASYMPTOMATIC
Prodromal period: mild symptoms appear
RUQ pain 2/2 hepatomegaly
fatigue
joint pain
Physical findings with HEP B?
hepatosplenomegaly
spider veins
jaundice
ascites
peripheral edema
How long is prodromal period of Hep B?
1-4 months
What is serum sickness in Hep B?
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