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GEORGE WASHINGTON UNIVERSITY, MLS 4141, IMMUNOLOGY AND SEROLOGY, CHAPTER 10 QUESTIONS AND CORRECT DETAILED ANSWERS (VERIFIED ANSWERS) ||ALREADY GRADED A+||NEWEST VERSION $13.49
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GEORGE WASHINGTON UNIVERSITY, MLS 4141, IMMUNOLOGY AND SEROLOGY, CHAPTER 10 QUESTIONS AND CORRECT DETAILED ANSWERS (VERIFIED ANSWERS) ||ALREADY GRADED A+||NEWEST VERSION
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  • Course
  • MLS 4141
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  • MLS 4141

Quiz: What is affinity? Ans: Attraction force between Fab site on Ab and epitope on Ag. Quiz: What does the strength of affinity depend on? Ans: Ag-Ab specificity. Quiz: What happens to affinity with a cross-reacting Ag? Ans: More the cross-reacting Ag resembles original Ag, stronger bond betw...

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  • January 21, 2025
  • 20
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

Subjects

  • george washington university mls 4141 immunolog

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  • MLS 4141
  • MLS 4141

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GEORGE WASHINGTON UNIVERSITY, MLS 4141,
IMMUNOLOGY AND SEROLOGY, CHAPTER 10
QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS) ||ALREADY
GRADED A+||NEWEST VERSION
Quiz: What is affinity?

Ans: Attraction force between Fab site on Ab and epitope on Ag.




Quiz: What does the strength of affinity depend on?

Ans: Ag-Ab specificity.




Quiz: What happens to affinity with a cross-reacting Ag?

Ans: More the cross-reacting Ag resembles original Ag, stronger bond between
Ag and binding site.




Quiz: What is avidity?




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Ans: Sum of attractive forces between Ag and Ab that hold molecule together.



Measures stability of Ag-Ab complex.




Quiz: What happens during a precipitation reaction?

Ans: Soluble Ag-Ab form a visible insoluble complex when they interact.




Quiz: What is required for a precipitation reaction?

Ans: Ag and Ab have multiple binding sites for each other.



Ag = Ab




Quiz: In order to be detectable, precipitation reactions must be run

in the...

Ans: Zone of equivalence.




Quiz: What are characteristics of the prozone?



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Ans: Ab excess, less Ag.

Ag only combines with 1-2 Abs.

NO CROSS LINKAGE




Quiz: Why can false negative reactions occur in the prozone?

Ans: High Ab concentration.

Dilution of Abs and performing test again may result in + test result.




Quiz: What are characteristics of the postzone?

Ans: Ag excess, less Ab.

Small aggregates surrounded by excess Ag.

NO LATTICE NETWORK




Quiz: Why can false negative reactions occur in the postzone?

Ans: Low Ab concentration.

Test must be repeated to give time for further production of Ab, and if it's still
negative, the patient doesn't have Ab.




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