MCB 2050 Final Exam Questions With Complete Solutions
__________________ facilitates ER to cis-Golgi
communication via a
direct interaction with the microtubules between these two
organelles. Correct Answers - Golgi Microtubule Associated
Protein-210 (GMAP-210)
* Other modifications to the core oligosaccharide in the Golgi
complex serve as a _______ _______ for proteins destined for
the lysosome.
* In the cis cisternae, ________ sugars in the core
oligosaccharide are phosphorylated.
* In the TGN - 'cargo' proteins with ____ group(s) are packaged
into lysosomal-destined transport vesicles.
* 'cargo' proteins without a M6P are packaged into other TGN
transport vesicles or granules destined for the pm (via the
secretory pathway) Correct Answers - targeting signal
- 2 mannose
- M6P
● All SNARE proteins possess a _______ ________. Correct
Answers - SNARE motif
● unique SNAREs are associated with _________ membranes.
Correct Answers - different
A CDK that controls the transition from G1 to S (START) and
G2 to M phase by binding to different cyclins is known as:
Correct Answers - CDC2
,A complex 'barrel shaped' multi subunit protein-degrading
machine located in the cytosol (and nucleus) is known as
________. Correct Answers - proteasome
A cytosolic-facing domain that extends from the
membrane surface; involved in SNARE-SNARE
protein binding is called a _________ _______. Correct
Answers - SNARE motif
A dynamic, coordinated network of all the cell's organelles and
related structures (except the mitochondria and chloroplasts) is
known as the: Correct Answers - endomembrane system
A GTP-binding protein that Has poor native GTPase activity
(can hydrolyze GTP to GDP and has poor ability to inactivate
itself) is: Correct Answers - Ran
A highly organized fluid-filled interior of the nucleus that
consists of more than 30 specialized regions (non-membrane
bound subdomains) with specific functions, is called what?
What does it contain? Correct Answers - nucleoplasm
- contains the nuclear matrix
A karyopherin (transport receptor) that mediates nucleus-to-
cytosol transport is known as an ___________. Correct
Answers - exportin
A pathway where materials are transported from the ER to the
Golgi, endosomes, then to either lysosomes (aka vacuoles in
plants and fungi/yeast) or to the plasma membrane (PM), is
called the: Correct Answers - biosynthetic pathway
,A protein required for plant pollination (involved in the
recognition of self incompatible protein) is called _________.
Correct Answers - ARC1
A ribonucleoparticle consisting of 6 proteins and 1 small RNA is
called the: Correct Answers - SRP
A Secretory Pathway where ER derived materials are
continually transported from the Golgi to the PM and/or released
(via exocytosis) outside of the cell (i.e. extracellular space) is
called a: Correct Answers - Constitutive Secretory Pathway
A Secretory Pathway which occurs only in specialized cells
where ER derived materials from the Golgi are stored in
secretory granules, is known as the: Correct Answers -
Regulated Secretory Pathway
A severe disease that results from mutations in the GMAP-210
gene, where Chondrocytes seem to be most affected is called?
Correct Answers - Achondrogenesis type 1A
A small protein that is involved in diverse cellular functions is
called _______. Correct Answers - Ubiquitin (Ub)
A Specific stretch/sequence of amino acids that are recognized
by exportin and serve as a zip code to mediate targeting of the
protein from the nucleus to the cytosol is known as
______________. Correct Answers - Nuclear Export Signals
(NES)
, A specific stretch/sequence of amino acids that are recognized
by the nuclear receptor proteins, contained by most nuclear-
imported proteins is called ________________.
There are several different types of these sequences based on
__________________. Correct Answers - Nuclear Localization
Signal (NLS)
- different unique amino acid sequences
A subcompartment of Golgi complex located at the Cis face of
the Golgi complex that Consists of interconnected network of
tubules and vesicles adjacent to the ERES is what?
What is the function of this subcompartment? Correct Answers
- Cis Golgi Network (CGN)
- serves as a 'sorting station'
A subcompartment of Golgi complex Located on the Trans face
of the Golgi Complex (upper face), and consists of
interconnected network of tubules and vesicles is called?
What is the function of this subcompartment? Correct Answers
- Trans Golgi Network (TGN)
- Serves as a sorting station by involving in the anterograde
transport of materials from the Golgi to other compartments in
the endomembrane system
A subcompartment of Golgi complex that is a Series of 3 or
more large, flattened cisternae that make up the majority of the
organelle is called?
What are the 3 main sections of this subcompartment?
__________________ facilitates ER to cis-Golgi
communication via a
direct interaction with the microtubules between these two
organelles. Correct Answers - Golgi Microtubule Associated
Protein-210 (GMAP-210)
* Other modifications to the core oligosaccharide in the Golgi
complex serve as a _______ _______ for proteins destined for
the lysosome.
* In the cis cisternae, ________ sugars in the core
oligosaccharide are phosphorylated.
* In the TGN - 'cargo' proteins with ____ group(s) are packaged
into lysosomal-destined transport vesicles.
* 'cargo' proteins without a M6P are packaged into other TGN
transport vesicles or granules destined for the pm (via the
secretory pathway) Correct Answers - targeting signal
- 2 mannose
- M6P
● All SNARE proteins possess a _______ ________. Correct
Answers - SNARE motif
● unique SNAREs are associated with _________ membranes.
Correct Answers - different
A CDK that controls the transition from G1 to S (START) and
G2 to M phase by binding to different cyclins is known as:
Correct Answers - CDC2
,A complex 'barrel shaped' multi subunit protein-degrading
machine located in the cytosol (and nucleus) is known as
________. Correct Answers - proteasome
A cytosolic-facing domain that extends from the
membrane surface; involved in SNARE-SNARE
protein binding is called a _________ _______. Correct
Answers - SNARE motif
A dynamic, coordinated network of all the cell's organelles and
related structures (except the mitochondria and chloroplasts) is
known as the: Correct Answers - endomembrane system
A GTP-binding protein that Has poor native GTPase activity
(can hydrolyze GTP to GDP and has poor ability to inactivate
itself) is: Correct Answers - Ran
A highly organized fluid-filled interior of the nucleus that
consists of more than 30 specialized regions (non-membrane
bound subdomains) with specific functions, is called what?
What does it contain? Correct Answers - nucleoplasm
- contains the nuclear matrix
A karyopherin (transport receptor) that mediates nucleus-to-
cytosol transport is known as an ___________. Correct
Answers - exportin
A pathway where materials are transported from the ER to the
Golgi, endosomes, then to either lysosomes (aka vacuoles in
plants and fungi/yeast) or to the plasma membrane (PM), is
called the: Correct Answers - biosynthetic pathway
,A protein required for plant pollination (involved in the
recognition of self incompatible protein) is called _________.
Correct Answers - ARC1
A ribonucleoparticle consisting of 6 proteins and 1 small RNA is
called the: Correct Answers - SRP
A Secretory Pathway where ER derived materials are
continually transported from the Golgi to the PM and/or released
(via exocytosis) outside of the cell (i.e. extracellular space) is
called a: Correct Answers - Constitutive Secretory Pathway
A Secretory Pathway which occurs only in specialized cells
where ER derived materials from the Golgi are stored in
secretory granules, is known as the: Correct Answers -
Regulated Secretory Pathway
A severe disease that results from mutations in the GMAP-210
gene, where Chondrocytes seem to be most affected is called?
Correct Answers - Achondrogenesis type 1A
A small protein that is involved in diverse cellular functions is
called _______. Correct Answers - Ubiquitin (Ub)
A Specific stretch/sequence of amino acids that are recognized
by exportin and serve as a zip code to mediate targeting of the
protein from the nucleus to the cytosol is known as
______________. Correct Answers - Nuclear Export Signals
(NES)
, A specific stretch/sequence of amino acids that are recognized
by the nuclear receptor proteins, contained by most nuclear-
imported proteins is called ________________.
There are several different types of these sequences based on
__________________. Correct Answers - Nuclear Localization
Signal (NLS)
- different unique amino acid sequences
A subcompartment of Golgi complex located at the Cis face of
the Golgi complex that Consists of interconnected network of
tubules and vesicles adjacent to the ERES is what?
What is the function of this subcompartment? Correct Answers
- Cis Golgi Network (CGN)
- serves as a 'sorting station'
A subcompartment of Golgi complex Located on the Trans face
of the Golgi Complex (upper face), and consists of
interconnected network of tubules and vesicles is called?
What is the function of this subcompartment? Correct Answers
- Trans Golgi Network (TGN)
- Serves as a sorting station by involving in the anterograde
transport of materials from the Golgi to other compartments in
the endomembrane system
A subcompartment of Golgi complex that is a Series of 3 or
more large, flattened cisternae that make up the majority of the
organelle is called?
What are the 3 main sections of this subcompartment?
