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This is a comprehensive and detailed practice material on;Nursing Interventions and Drug Information for Mental Health Medications. An Essential Study Resource just for YOU!!

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  • February 20, 2025
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  • 2023/2024
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Drug Action and Interaction Complications Nursing Interventions

Benzodiazepine Sedative Hypnotic Anxiolytics

Alprazolam Use for Anxiety Disorders - CNS depression: - Avoid abrupt discontinuation to prevent
Benzodiazepines enhance the - Sedation withdrawal manifestations.
Diazepam inhibitory effects of - Lightheadedness - Taper the dose over several weeks using
gamma-aminobutyric acid in the CNS, Relief - Ataxia (impaired balance/ coordination) prescribed dosing schedule.
Lorazepam from anxiety occurs rapidly following - Decreased Cognitive Function - Take meds with meals or snacks if GI upset
administration. occurs.
Chlordiazepoxide - Swallow sustained-release tablets and avoid
Anterograde Amnesia:
Contraindication: - difficulty recalling events that occur after chewing or crushing the tablets.
Oxazepam - Pregnancy and breastfeeding dosing
- Sleep Apnea CNS Depression:
Clonazepam
- Respiratory Depression Acute Toxicity: (oral) - Avoid hazardous activities (driving, operating
- Glaucoma - Drowsiness, Lethargy, Confusion heavy equipment/machinery)
- Use cautiously in patients with Liver -Avoid concurrent use of alcohol and other CNS
Disease or HX of substance use disorder. Acute Toxicity: (IV) depressants.
- Respiratory depression, Severe
Other Uses: hypotension, cardiac arrest Acute Toxicity:
- Seizures - For Oral toxicity, gastric lavage is used, followed
- Insomnia by activated charcoal or saline cathartics. - Antidote:
Paradoxical response: (opposite response)
- Muscle spasm Flumazenil is administered to
-Insomnia -Excitation -Euphoria -Anxiety
counteract sedation and reverse adverse effects. -
- Alcohol withdrawal -Rage
Monitor V/S, maintain patent airway, provide fluids to
- Induction of Anesthesia
maintain blood pressure.
- Amnesic prior to surgery
- Ensure availability of resuscitation equipment.

Withdrawal effects:
**IMPORTANT**
- Anxiety, Insomnia, Diaphoresis, Tremors,
- First-line of treatment for Generalized
Lightheadedness, Delirium, Seizures
Anxiety Disorders and Panic Disorders
-Benzos are classified under schedule IV of the
Controlled Substances Act

,Drug Action and Interaction Complications Nursing Interventions

,Atypical Anxiolytic / Nonbarbiturate Anxiolytics

, Buspirone For Anxiety Disorders CNS effects: - take with meals to prevent gastric irritation
- this medication binds to serotonin
- Dizziness - take two doses in morning and evening - can
and dopamine receptors.
- Nausea take a week to notice first therapeutic effects and 2 to 6
- use of buspirone does NOT result in
sedation or potentiate the effects of other - Headache weeks to reach full therapeutic benefit. take it on a
CNS depressants. It carries no risk of abuse. - Lightheadedness regular basis.
- Anti Anxiety effects develop slowly. -
- Agitation
Initial response takes 1 week and at least 2 to
6 weeks for it to reach its full effects. **needs
to be taken on a scheduled basis**
**Buspirone does not interfere with activities
Contraindications: because it does not cause sedation.
- Pregnancy and breastfeeding
- Liver and Kidney dysfunction ** AVOID St. John’s Wort, Erythromycin,
Ketoconazole and Grapefruit can increase
- DO NOT use MAOI antidepressants,
the effects of buspirone.
or for 14 days after MAOIs are discontinued.
Hypertensive Crisis can result.

**IMPORTANT**
- Buspirone has less potential for
dependency than other Anxiolytics.

- Withdrawal manifestations are not
an issue with this medication.

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