Post-strep glomerulonephritis
Study online at https://quizlet.com/_empsy8
1. What is post-strep glomeru- Type 3 hypersensitivity reaction after a streptococcus infec-
lonephritis? tion that causes immune system complexes to be deposited
in the glomerulus
2. What causes post-strep Group A and B haemolytic strep
glomerulonephritis?
3. What is usually the timeframe usually ~2 weeks after S pyogenes infection
of infection leading to glomeru-
lonephritis? How does this differ IgA - 1-2 days post viral infection
to IgA nephropathy?
4. What symptoms does post strep Visible haematuria!!!
glomerulonephritis cause? Oligouria
HTN
Mild proteinuria
Px usually young too
5. How is post-streptococcal Light - thicker glomerular basement membrane
glomerulonephritis diagnosed? Electron - sub-podocyte immune deposition
How does this differ between
electron and light microscopy?
6. How is post-streptococcus Is usually self-limiting
glomerulonephritis treated?
Can give Abx, ACE-i and diuretics
7. What is RPGN? How is it diag- Rapidly progressive glomerulonephritis - progresses to ESRF
nosed? within weeks-months
Biopsy showing inflammatory crescents in Bowmann's space
1/2
Study online at https://quizlet.com/_empsy8
1. What is post-strep glomeru- Type 3 hypersensitivity reaction after a streptococcus infec-
lonephritis? tion that causes immune system complexes to be deposited
in the glomerulus
2. What causes post-strep Group A and B haemolytic strep
glomerulonephritis?
3. What is usually the timeframe usually ~2 weeks after S pyogenes infection
of infection leading to glomeru-
lonephritis? How does this differ IgA - 1-2 days post viral infection
to IgA nephropathy?
4. What symptoms does post strep Visible haematuria!!!
glomerulonephritis cause? Oligouria
HTN
Mild proteinuria
Px usually young too
5. How is post-streptococcal Light - thicker glomerular basement membrane
glomerulonephritis diagnosed? Electron - sub-podocyte immune deposition
How does this differ between
electron and light microscopy?
6. How is post-streptococcus Is usually self-limiting
glomerulonephritis treated?
Can give Abx, ACE-i and diuretics
7. What is RPGN? How is it diag- Rapidly progressive glomerulonephritis - progresses to ESRF
nosed? within weeks-months
Biopsy showing inflammatory crescents in Bowmann's space
1/2