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OPT 223 Retinal Treatments Exam With Correct Answers!!
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OPT 223 Retinal Treatments Exam With Correct Answers!!What was the purpose of the BVOS: Branch Vein Occlusion Study (1977)?
evaluate the following BRVO tx...
1. argon grid macular laser photocoagulation for macular edema
2. sectoral argan scatter PRP for neovasc/vitreous heme
What was the outcome of the BVOS: Branch Vein Occlusion Study (1977)?
both laser photocoagulation (for macular edema) and scatter PRP (for neo) become the
gold standard tx to help/save vision
What was the purpose of the CVOS: Central Vein Occlusion Study (1988-94)?
evaluate macular grid laser photocoagulation to treat macular edema from CRVO
What was the outcome of the CVOS: Central Vein Occlusion Study (1988-94)?
did NOT support macular grid laser for macular edema from CRVO (vision did not help)
,NOTE: opposite of BRVO study
What was the purpose of the SCORE: Standard Care vs Corticosteroid for Retinal Vein
Occlusion Study (2009)?
evaluate intravitreal triamcinolone steroid to treat macular edema from CRVO and
BRVO
What were the 2 arms of the SCORE: Standard Care vs Corticosteroid for Retinal Vein
Occlusion Study (2009)?
arm 1 = CRVO = monitor vs triamcinolone 1 mg vs triamcinolone 4 mg
arm 2 = BRVO = laser photocoagulation vs triamcinolone 1 mg vs triamcinolone 4 mg
What were the outcomes of the 2 arms of the SCORE: Standard Care vs Corticosteroid
for Retinal Vein Occlusion Study (2009)?
arm 1 = CRVO = triamcinolone resulted in the best gain in VA lines (compared to
monitoring)
arm 2 = BRVO = laser photocoagulation resulted in the best gain in VA lines (compared
to triamcinolone)
, Triamcilonone injectable steroid was never FDA approved for macular edema from
CRVO/BRVO because of what 2 side effects?
glaucoma from high IOP
PSC cataracts
While triamcilonone can still be used off-label for macular edema from CRVO/BRVO,
what is the ONLY FDA approved steroid tx for RVO-related macular edema?
dexamethasone (Ozurdex 2009)
What was the standard of care for RVO-related macular edema until anti-VEGF was
invented?
laser photocoagulation
What was the purpose of the BRAVO: Ranibizumab Injection in Pt's with Macular Edema
Secondary to BRVO (2011)?
evaluate intravitreal ranibizumab (anti-VEGF) for treating macular edema associated
with BRVO - 3 tx groups:
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