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Nagelhout Pharm 2 Exam 3 Questions and Answers Already Graded A

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Class III antiarrhythmics - ANSWER-K channel blockers (prolongs depolarization) (amiodarone) Class IV antiarrhythmic - ANSWER-Calcium channel blocker (verapamil, diltiazem) adenosine works on what kind of receptor? - ANSWER-purinergic receptors 3 populations to be cautious of beta blockers...

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  • March 21, 2025
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IMORA
Nagelhout Pharm 2 Exam 3 Questions and
Answers Already Graded A


Class I antiarrhythmics - ANSWER-Sodium channel blockers (procainamide, lidocaine)

Class II antiarrhythmics - ANSWER-Beta blockers (propranolol)

Class III antiarrhythmics - ANSWER-K channel blockers (prolongs depolarization)
(amiodarone)

Class IV antiarrhythmic - ANSWER-Calcium channel blocker (verapamil, diltiazem)

adenosine works on what kind of receptor? - ANSWER-purinergic receptors

3 populations to be cautious of beta blockers in - ANSWER-asthmatics (cause
bronchoconstriction), diabetics (cause hypoglycemia), this with claudication

drug of choice for A-fib/flutter - ANSWER-CCB-diltiazem
alternate: beta blocker

drug of choice for ventricular arrhythmias - ANSWER-amiodarone (K-blocker);
alternate: lido

drug of choice for torsades - ANSWER-magnesium

drug of choice for bradycardia - ANSWER-atropine

drug of choice for tachycardia - ANSWER-beta-blocker

how to you treat dig toxicity - ANSWER-treat however it presents- like a normal
arrhythmia (atrial vs ventricular etc)

BP Category: Normal - ANSWER-SBP <120 and DBP <80

BP Category: Elevated - ANSWER-SBP: 120-129 and DBP <80

BP Category: HTN Stage 1 - ANSWER-SBP:130-139 or DBP: 80-89

BP Category: HTN Stage 2 - ANSWER-SBP: >140 or DBP:>90

Hypertensive crisis - ANSWER-SBP>180 or DBP>120

, Definition: Hypertensive urgency - ANSWER-hypertensive urgency- the a patient comes
to medical attention with severe hypertension (SBP>180 or DBP >120) but does not
have associated acute end organ damage of the CNS, CV system or kidneys
reduce BP over hours to days

Definition: Hypertensive Emergency - ANSWER-hallmark: presence of acute end organ
damage and high degree of BP elevation. End-organ damage is the result of acute rise
in BP
treatment in Minutes- hours to prevent morbidity/mortality

Definition: Hypertensive crisis - ANSWER-more reflective of the high degree of BP
elevation

3 primary systems in the body to maintain BP - ANSWER-autonomic nervous system
(catecholamines--> increased B in kidneys which increases renin--> RAAS)
RAAS
vasopressin
- when you stimulate one, you stimulate them all

How do ACE-I work? - ANSWER-preventing the conversion of angiotensin I to
angiotensin II

how do ACE-I cause cough - ANSWER-bradykinin is broken down by ACE; ACE-I
increases bradykinin--> cough

how do ARBs work? - ANSWER-ARBs work by blocking the angiotensin receptor
blocker

Esmolol vs Labetalol - ANSWER-Labetalol:
-is a B and a blocker--> vasodilation
-not cardioselective
-preferred for HTN
Esmolol
-just a B blocker--> vasoconstriction
-shorter acting (broken down by RBC esterase in the plasma)
- "cardioselective" (not really)
-preferred for tachycardia

how does nitroprusside work? - ANSWER-its part of the nitro group so it vasodilates

how is nitroprusside metabolized? - ANSWER-by hemoglobin

how is nitroprusside eliminated? - ANSWER-It goes to the liver. Rhodanese causes
cyanide to act with vitamin B 12 to become thiocyanate which you pee out

What is cyanide poisoning? How is it toxic to the body? - ANSWER-Cyanide poisoning
happens when there is too much cyanide or not enough vitamin B12. It goes into the

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