MCDB 1A FINAL PRACTICE EXAM
QUESTIONS WITH VERIFIED
SOLUTIONS
Imagine you have an mRNA molecule that encodes a protein 368 AA long. Which is
most likely to have MOST SEVERE consequences for ability of the resulting protein to
function? - Correct Answers -The ERROR of the DELETION of one nucleotide at 301st
codon
In the Hershey chase experiment in which P32 was used to label DNA, what part of the
DNA became radioactive? - Correct Answers –BACKBONE
Consider the transcription bubble. Note that the gene encoding hemoglobin is located at
right of the bubble and that RNA polymerase is in the middle of the bubble. If this were a
blood cell that needed to synthesize hemoglobin, which STRAND IS TEMPLATE for
TRANSCRIPTION? - Correct Answers -UPPER
Recall Meselson- Stahl in which cells were grown in N-14 and N-15. What was the main
question being asked in experiment? - Correct Answers -Do the two strands of DNA
separate form one another during replication?
If human liver cells have 21% C in their RNA, how much U s present in liver RNA? -
Correct Answers -NO WAY TO KNOW
The most commonly occurring mutation in people with cystic fibrosis is a deletion of a
single codon. What is the result of this type of mutation? - Correct Answers -
POLYPEPTIDE missing an Amino Acid
In the year 1944 Avery transformation experiment utilizing DNase, RNase, and
protease, which of the following observations was most important in supporting the
conclusion that DNA was a genetic MATERIAL? - Correct Answers -Treatment of the
extract with DNase prevented transformation of R to S cells
Semiconservative replication involves a template. What is the template for replication? -
Correct Answers -ONE STRAND of the DNA molecule
Which of the following statements describes the process of transformation in bacteria? -
Correct Answers -external DNA is taken INTO CELL, becoming part of cell's GENOME
QUESTIONS WITH VERIFIED
SOLUTIONS
Imagine you have an mRNA molecule that encodes a protein 368 AA long. Which is
most likely to have MOST SEVERE consequences for ability of the resulting protein to
function? - Correct Answers -The ERROR of the DELETION of one nucleotide at 301st
codon
In the Hershey chase experiment in which P32 was used to label DNA, what part of the
DNA became radioactive? - Correct Answers –BACKBONE
Consider the transcription bubble. Note that the gene encoding hemoglobin is located at
right of the bubble and that RNA polymerase is in the middle of the bubble. If this were a
blood cell that needed to synthesize hemoglobin, which STRAND IS TEMPLATE for
TRANSCRIPTION? - Correct Answers -UPPER
Recall Meselson- Stahl in which cells were grown in N-14 and N-15. What was the main
question being asked in experiment? - Correct Answers -Do the two strands of DNA
separate form one another during replication?
If human liver cells have 21% C in their RNA, how much U s present in liver RNA? -
Correct Answers -NO WAY TO KNOW
The most commonly occurring mutation in people with cystic fibrosis is a deletion of a
single codon. What is the result of this type of mutation? - Correct Answers -
POLYPEPTIDE missing an Amino Acid
In the year 1944 Avery transformation experiment utilizing DNase, RNase, and
protease, which of the following observations was most important in supporting the
conclusion that DNA was a genetic MATERIAL? - Correct Answers -Treatment of the
extract with DNase prevented transformation of R to S cells
Semiconservative replication involves a template. What is the template for replication? -
Correct Answers -ONE STRAND of the DNA molecule
Which of the following statements describes the process of transformation in bacteria? -
Correct Answers -external DNA is taken INTO CELL, becoming part of cell's GENOME
