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• Chamberlain NR507 Midterm Exam Study Guide | Advanced Pathophysiology | 2025/2026 Verified

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• Chamberlain NR507 Midterm Exam Study Guide | Advanced Pathophysiology | 2025/2026 Verified

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Pathophysiology
Course
Pathophysiology










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Institution
Pathophysiology
Course
Pathophysiology

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Uploaded on
April 3, 2025
Number of pages
18
Written in
2024/2025
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1. A patient with a history of gout presents with severe joint pain
in the big toe. What is the most likely cause of this pain?
A. Hyperuricemia
B. Osteoarthritis
C. Rheumatoid arthritis
D. Bone fracture
Answer: A) Hyperuricemia
Rationale: Gout is caused by the accumulation of uric acid crystals
in the joints, often beginning with the big toe. Elevated uric acid
levels (hyperuricemia) lead to these crystals forming and causing
intense pain.

2. Which of the following is a primary complication of untreated
hypertension?
A. Diabetes
B. Stroke
C. Asthma
D. Hyperthyroidism
Answer: B) Stroke
Rationale: Untreated hypertension can cause damage to blood
vessels, increasing the risk of a stroke due to the development of
atherosclerosis or rupture of a weakened vessel.

3. In which of the following conditions would you expect an
increase in erythrocyte sedimentation rate (ESR)?
A. Acute inflammation
B. Dehydration
C. Iron deficiency anemia
D. Chronic hypertension
Answer: A) Acute inflammation
Rationale: ESR is an indicator of inflammation. It increases during

,acute inflammatory processes, such as infections, autoimmune
diseases, and other inflammatory conditions.

4. What is the primary cause of osteoarthritis?
A. Autoimmune reaction
B. Wear and tear on the joints
C. Bacterial infection
D. Vitamin D deficiency
Answer: B) Wear and tear on the joints
Rationale: Osteoarthritis is primarily caused by the degeneration
of cartilage due to repetitive use or aging, leading to joint pain
and stiffness.

5. A patient with acute bacterial meningitis is likely to experience
which of the following?
A. Increased thirst and urination
B. Severe headache and neck stiffness
C. Joint pain and swelling
D. Abdominal pain and bloating
Answer: B) Severe headache and neck stiffness
Rationale: Acute bacterial meningitis causes inflammation of the
meninges, leading to symptoms like severe headache, neck
stiffness, photophobia, and fever.

6. What is the main cause of liver cirrhosis?
A. Alcohol abuse
B. High-fat diet
C. Viral infections (e.g., hepatitis B or C)
D. Obesity
Answer: A) Alcohol abuse
Rationale: Chronic alcohol use is the leading cause of cirrhosis,
leading to liver fibrosis and eventual liver failure.

, 7. A nurse is caring for a patient with rheumatoid arthritis. Which
of the following is a common manifestation of this condition?
A. Symmetrical joint pain and swelling
B. Morning dizziness and fatigue
C. Unilateral leg swelling
D. Chest pain
Answer: A) Symmetrical joint pain and swelling
Rationale: Rheumatoid arthritis typically causes symmetrical joint
pain, stiffness, and swelling, particularly in the hands and feet.

8. A patient is being treated for acute pancreatitis. What is a
common complication of this condition?
A. Renal failure
B. Chronic diarrhea
C. Hyperglycemia
D. Gallstones
Answer: A) Renal failure
Rationale: Acute pancreatitis can lead to systemic complications,
including renal failure, due to inflammation and the release of
digestive enzymes into the bloodstream.

9. Which of the following is a common sign of hypovolemic
shock?
A. Bradycardia
B. Tachycardia
C. Warm skin
D. Hypertension
Answer: B) Tachycardia
Rationale: In hypovolemic shock, blood volume decreases, and the
body compensates by increasing the heart rate (tachycardia) to
maintain blood flow to vital organs.

10. A patient with a diagnosis of schizophrenia may experience

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