Nature debate
gene and heredity factors; physical appearance to personality and behavior
Nurture debate
environmental variables including early childhood, social relationships, surrounding
culture
Human Genome Project
project whose goal is to map, sequence, and identify all of the genes in the human
genome
Genetic determinism
idea that genes determine our behavior, thoughts, emotions, and social characteristics
Most of the genetic variation that could influence health outcomes do so through
interactions between....
the external and internal environment
Epigenetics
the study of gene-environment interaction; heritable changes in gene expression (active
vs inactive) that do not involve changes in the underlying DNA sequence
Epigenetic mechanisms
chemical processes that affect how your genes shape you as a person where those
chemical processes are influenced by environmental factors
Genotype
organisms complete set of heritable genes
Phentoype
observable characteristics
Changes in gene expression
DO NOT involve changes to the underlying DNA sequence
Exposome
A measure of all the exposures to a person during a lifetime and how those exposures
relate to personal health, such as risk to disease.
DNA methylation
, tags DNA and activates or represses genes
the environment-gene interaction...
allows organisms to adapt to different environments through the feedback loop inherit to
the process
histone or chromatin modification
binding of epigenetic factors to histone "tails" alters the extent to which DNA is wrapped
around histone and the availability of genes in DNA to be activated
aggregated factors
exposome in epigenetics
disparity exposome
health disparity communities are exposed to higher levels of the environmental factors
that produce epigenetic changes associated with health risks
implication connected to epigenetics
1. prevention (access to parental and early childcare, reducing poverty, reducing
unhealthy environment exposure)
2. reversing epigenetic changes (parent interventions, family and community violence
interventions)
3. mitigation (social support)
What are the three steps to planning approaches for PRECEDE-PROCEED and the
Risk and Protective factors planning model?
1. Assessment
2. Development of intervention
3. Evaluation
Precede-Proceed Model
Consists of eight phases that provide a framework for intervention. It is an educational
and ecologic model that incorporates planning for evidence-based best practices,
interventions, and integration of evaluation methods for improvement of quality.
(focuses on community or local level)
what does PRECEDE and PROCEED stand for
Predisposing Reinforcing and Enabling Constructs in
Educational/environmental Diagnosis and Evaluation.
Policy Regulatory and Organizational Constructs in Educational and Environmental
Development.
Phase 1 of Precede-Proceed
social assessment and situational analysis
-assessment of quality of life and social factors