USMLE Step 2 Rapid Review 2025/2026
Exam Questions Marking Scheme New
Update | A+ Rated
"Sawtooth" P waves - 🧠 ANSWER ✔✔Classic ECG finding in atrial flutter.
Angina is new, is worsening, or occurs at rest - 🧠 ANSWER ✔✔Definition of
unstable angina.
ACEI - 🧠 ANSWER ✔✔Antihypertensive for a diabetic patient with
proteinuria.
Hypotension, distant heart sounds, and JVD - 🧠 ANSWER ✔✔Beck's triad
for cardiac tamponade.
β-blockers, digoxin, calcium channel blockers - 🧠 ANSWER ✔✔Drugs that
slow AV node transmission.
Niacin - 🧠 ANSWER ✔✔Hypercholesterolemia treatment that → flushing
and pruritus.
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STATEMENT. ALL RIGHTS RESERVED
,Anticoagulation, rate control, cardioversion - 🧠 ANSWER ✔✔Treatment for
atrial fibrillation.
Immediate cardioversion - 🧠 ANSWER ✔✔Treatment for ventricular
fibrillation.
Dressler's syndrome: fever, pericarditis, ↑ ESR - 🧠 ANSWER
✔✔Autoimmune complication occurring 2-4 weeks post-MI.
Treat existing heart failure and replace the tricuspid valve - 🧠 ANSWER
✔✔IV drug use with JVD and holosystolic murmur at the left sternal border.
Treatment?
Echocardiogram (showing thickened left ventricular wall and outflow
obstruction) - 🧠 ANSWER ✔✔Diagnostic test for hypertrophic
cardiomyopathy.
Pulsus paradoxus (seen in cardiac tamponade) - 🧠 ANSWER ✔✔A fall in
systolic BP of > 10 mmHg with inspiration.
Low-voltage, diffuse ST-segment elevation - 🧠 ANSWER ✔✔Classic ECG
findings in pericarditis.
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2
STATEMENT. ALL RIGHTS RESERVED
,BP > 140/90 on three separate occasions two weeks apart - 🧠 ANSWER
✔✔Definition of hypertension.
Renal artery stenosis, coarctation of the aorta, pheochromocytoma, Conn's
syndrome, Cushing's syndrome, unilateral renal parenchymal disease,
hyperthyroidism, hyperparathyroidism - 🧠 ANSWER ✔✔Eight surgically
correctable causes of hypertension.
Abdominal ultrasound and CT - 🧠 ANSWER ✔✔Evaluation of a pulsatile
abdominal mass and bruit.
> 5.5 cm, rapidly enlarging, symptomatic, or ruptured - 🧠 ANSWER
✔✔Indications for surgical repair of abdominal aortic aneurysm.
Morphine, O2, sublingual nitroglycerin, ASA, IV β-blockers, heparin - 🧠
ANSWER ✔✔Treatment for acute coronary syndrome.
Abdominal obesity, high triglycerides, low HDL, hypertension, insulin
resistance, prothrombotic or proinflammatory states - 🧠 ANSWER ✔✔What
is the metabolic syndrome?
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3
STATEMENT. ALL RIGHTS RESERVED
, Exercise stress treadmill with ECG - 🧠 ANSWER ✔✔Appropriate diagnostic
test? ■ A 50-year-old male with angina can exercise to 85% of maximum
predicted heart rate.
Pharmacologic stress test (e.g., dobutamine echo) - 🧠 ANSWER
✔✔Appropriate diagnostic test? ■ A 65-year-old woman with left bundle
branch block and severe osteoarthritis has unstable angina.
Angina, ST-segment changes on ECG, or ↓ BP - 🧠 ANSWER ✔✔Signs of
active ischemia during stress testing.
ST-segment elevation (depression means ischemia), flattened T waves,
and Q waves - 🧠 ANSWER ✔✔ECG findings suggesting MI.
Prinzmetal's angina - 🧠 ANSWER ✔✔A young patient has angina at rest
with ST-segment elevation. Cardiac enzymes are normal.
CHF, shock, and altered mental status - 🧠 ANSWER ✔✔Common
symptoms associated with silent MIs.
V/Q scan - 🧠 ANSWER ✔✔The diagnostic test for pulmonary embolism.
Protamine - 🧠 ANSWER ✔✔An agent that reverses the effects of heparin.
PT - 🧠 ANSWER ✔✔The coagulation parameter affected by warfarin.
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
4
STATEMENT. ALL RIGHTS RESERVED
Exam Questions Marking Scheme New
Update | A+ Rated
"Sawtooth" P waves - 🧠 ANSWER ✔✔Classic ECG finding in atrial flutter.
Angina is new, is worsening, or occurs at rest - 🧠 ANSWER ✔✔Definition of
unstable angina.
ACEI - 🧠 ANSWER ✔✔Antihypertensive for a diabetic patient with
proteinuria.
Hypotension, distant heart sounds, and JVD - 🧠 ANSWER ✔✔Beck's triad
for cardiac tamponade.
β-blockers, digoxin, calcium channel blockers - 🧠 ANSWER ✔✔Drugs that
slow AV node transmission.
Niacin - 🧠 ANSWER ✔✔Hypercholesterolemia treatment that → flushing
and pruritus.
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
1
STATEMENT. ALL RIGHTS RESERVED
,Anticoagulation, rate control, cardioversion - 🧠 ANSWER ✔✔Treatment for
atrial fibrillation.
Immediate cardioversion - 🧠 ANSWER ✔✔Treatment for ventricular
fibrillation.
Dressler's syndrome: fever, pericarditis, ↑ ESR - 🧠 ANSWER
✔✔Autoimmune complication occurring 2-4 weeks post-MI.
Treat existing heart failure and replace the tricuspid valve - 🧠 ANSWER
✔✔IV drug use with JVD and holosystolic murmur at the left sternal border.
Treatment?
Echocardiogram (showing thickened left ventricular wall and outflow
obstruction) - 🧠 ANSWER ✔✔Diagnostic test for hypertrophic
cardiomyopathy.
Pulsus paradoxus (seen in cardiac tamponade) - 🧠 ANSWER ✔✔A fall in
systolic BP of > 10 mmHg with inspiration.
Low-voltage, diffuse ST-segment elevation - 🧠 ANSWER ✔✔Classic ECG
findings in pericarditis.
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
2
STATEMENT. ALL RIGHTS RESERVED
,BP > 140/90 on three separate occasions two weeks apart - 🧠 ANSWER
✔✔Definition of hypertension.
Renal artery stenosis, coarctation of the aorta, pheochromocytoma, Conn's
syndrome, Cushing's syndrome, unilateral renal parenchymal disease,
hyperthyroidism, hyperparathyroidism - 🧠 ANSWER ✔✔Eight surgically
correctable causes of hypertension.
Abdominal ultrasound and CT - 🧠 ANSWER ✔✔Evaluation of a pulsatile
abdominal mass and bruit.
> 5.5 cm, rapidly enlarging, symptomatic, or ruptured - 🧠 ANSWER
✔✔Indications for surgical repair of abdominal aortic aneurysm.
Morphine, O2, sublingual nitroglycerin, ASA, IV β-blockers, heparin - 🧠
ANSWER ✔✔Treatment for acute coronary syndrome.
Abdominal obesity, high triglycerides, low HDL, hypertension, insulin
resistance, prothrombotic or proinflammatory states - 🧠 ANSWER ✔✔What
is the metabolic syndrome?
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
3
STATEMENT. ALL RIGHTS RESERVED
, Exercise stress treadmill with ECG - 🧠 ANSWER ✔✔Appropriate diagnostic
test? ■ A 50-year-old male with angina can exercise to 85% of maximum
predicted heart rate.
Pharmacologic stress test (e.g., dobutamine echo) - 🧠 ANSWER
✔✔Appropriate diagnostic test? ■ A 65-year-old woman with left bundle
branch block and severe osteoarthritis has unstable angina.
Angina, ST-segment changes on ECG, or ↓ BP - 🧠 ANSWER ✔✔Signs of
active ischemia during stress testing.
ST-segment elevation (depression means ischemia), flattened T waves,
and Q waves - 🧠 ANSWER ✔✔ECG findings suggesting MI.
Prinzmetal's angina - 🧠 ANSWER ✔✔A young patient has angina at rest
with ST-segment elevation. Cardiac enzymes are normal.
CHF, shock, and altered mental status - 🧠 ANSWER ✔✔Common
symptoms associated with silent MIs.
V/Q scan - 🧠 ANSWER ✔✔The diagnostic test for pulmonary embolism.
Protamine - 🧠 ANSWER ✔✔An agent that reverses the effects of heparin.
PT - 🧠 ANSWER ✔✔The coagulation parameter affected by warfarin.
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
4
STATEMENT. ALL RIGHTS RESERVED
