Een handige korte samenvatting over de verschillende medicatiesoorten die gebruikt worden bij hartaandoeningen. Diuretica komen kort aan bod, echter niet uitgebreid daar deze medicatie in de nieren werkt.
Diuretica
- HCT (hydrochloorthiazide), Furosemide, Spironolacton
- Zorgen voor meer urineproductie RR daalt
Sympathicus remmers
Bètablokkers
- Eindigen op -olol (Metoprolol, Propranolol)
- Blokkeert β1 en/of β2 receptor gevoeligheid van weefsel neemt af
- Effect = verlaging hartslagfrequentie en hartminuutvolume (RR daalt), remming van renine afgifte
(angiotensine 2 neemt af RR daalt), vertraging van AV-geleiding (bij AF).
- Bijwerkingen: bradycardie, (orthostatische) hypotensie, koude handen en voeten, vermoeidheid,
slaapstoornissen (incl. slapeloosheid en nachtmerries), depressie, duizeligheid.
- Indicatie: hypertensie, AF, onderhoudsbehandeling stabiele AP, hartfalen, behandeling NSTEMI,
migraine.
Vasoconstrictie remmer
Calcium antagonisten (dihydropyridinen)
- Eindigen op -dipine (Nifedipine, Amlodipine)
- Verminderen de contractie van vooral glad spierweefsel van perifere en coronaire arteriën.
- Effect = verlaging bloeddruk, vasodilatatie
- Bijwerkingen: duizeligheid; blozen; hoofdpijn; hypotensie; perifeer oedeem; gastro-oesofageale
reflux.
- Indicatie: hypertensie, fenomeen van Raynaud, onderhoudsbehandeling bij stabiele AP.
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