NURS 5315
Chamberlain College Nursing
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N5315 Advanced Pathophysiology Cancer Module Objectives with Advanced Organizers
- Exam (elaborations) • 7 pages • 2022
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Examine the basic concepts of cancer nomenclature and biology. 
a. Identify the cancer types which produce the tumor markers alpha fetoprotein, 
carcinoembryonic antigen, beta human chorionic gonadotropin, and prostate 
specific antigen. 
Tumor Marker Origin 
Alpha Fetoprotein Liver and Germ Cells 
Carcinoembryonic Antigen GI, Pancreas, Lung, Breast, etc 
Beta Human Chorionic 
gonadotropin 
Germ Cells 
Prostate Specific Antigen Prostate 
b. Identify the origins of a cancer based on the following...
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N5315 Advanced Pathophysiology Inflammation, Altered Immunity and Infection Core Concepts Objectives with Advanced Organizers
- Exam (elaborations) • 23 pages • 2022
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Examine the structure and function of the immune system. 
a. Describe how the normal function of T-lymphocyte and B-lymphocyte cells differ. 
i. T Cells- Cell mediated immunity. 
1. “cluster of differentiation” 
2. CD4 cells- t-helper or t4 cells 
a. Release lymphokines to begin inflammatory process 
b. Mediate delayed sensitivity. (TB skin test). 
3. CD8 cells aka t cells, killer t, and t8. 
a. Kill viruses by releasing cytotoxic chemicals 
4. Memory T 
a. Remember the antigen and respond q...
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N5315 Advanced Pathophysiology Altered Cellular Function and Cancer Module Core Concepts and Objectives with Advanced Organizers
- Exam (elaborations) • 23 pages • 2022
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Cellular Physiology 
1. Analyze the steps of the action potential. 
● Sodium permeability increases, sodium ions move into the cell increasing positivity, 
depolarization is occurring, action potential threshold is reached as cell becomes more 
positive, potassium permeability increases, potassium ions leave the cell, repolarization is 
occurring, resting membrane potential is reestablished. 
· The action potential carries signals along the nerve or muscle cell and conveys 
information from o...
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N5315 Advanced Pathophysiology Altered Cellular Function and Cancer Module Core Concepts and Objectives with Advanced Organizers
- Exam (elaborations) • 58 pages • 2022
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N5315 Advanced Pathophysiology 
Altered Cellular Function and Cancer 
Module Core Concepts and Objectives with Advanced Organizers 
Cellular Physiology 
1. Analyze the steps of the action potential. 
● Sodium permeability increases, sodium ions move into the cell increasing positivity, 
depolarization is occurring, action potential threshold is reached as cell becomes more 
positive, potassium permeability increases, potassium ions leave the cell, repolarization is 
occurring, resting membrane...
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N5315 Advanced Pathophysiology Fluid and Electrolytes Core Concept and Objectives with Advanced Organizers
- Exam (elaborations) • 14 pages • 2022
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1. Analyze the pathologic consequences of fluid volume disorders on the mechanisms of 
fluid homeostasis. 
a. Explain the three main fluid compartments and describe how fluid shifts between 
the compartments and the implications for clinical practice. 
Total body water is approximately 60% of the body weight and is spread between 
the three main fluid compartments. 
Fluid Compartments Definition Pattern of Fluid Shifts Clinical Implications 
Intravascular 
Main ECF compartment 
The intravascular...
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