NR511 Midterm Study Guide
Harvard University
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Exam (elaborations) NR511 MIDTERM STUDY GUIDE
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Exam (elaborations) NR511 MIDTERM STUDY GUIDE 
Actinic keratosis most common precancerous skin lesion in light skinned patients, more common in patients 
50 years or older (most common in Celtic, Irish, and Scottish descent) 
 
Found in sun exposed areas 
 
Caused by skin cells that accumulate from repeated sun exposure 
 
Pathophys: continued sun damage from UV radiation damages the DNA in epithelial cells 
 
Primary lesions: macules or plaques, poorly circumscribed 
Secondary lesion...
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