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SBB QuestionsThe Donath-Landsteiner test attempts to detect clinically significant antibodies related to a rare disorder called paroxysmal cold hemoglobinuria. The specificity of this biphasic antibody is directed towards: 
A. K1 
B. P,P1,Pk Glycolipid(Globosides) C.P,P1,Pk Glycophorin 
D. P,P1,Pk Glycoprotein 
E. Parvo B19 
F. p` antigen - correct answer B.P,P1,Pk Glycolipid(Globosides) C.P,P1,Pk Glycophorin 
 
The Donath-Landsteiner antibody is characterized by the following clinically signifi...
SBB ReviewBand 3 - correct answer macrocomplex of proteins including: 
-Rh 
-RhAG 
-LW (ICAM-4) 
-GPA 
-GPB 
-CD47 
 
ATP source for RBCs - correct answer 90% from Glycolysis (Embden-Meyerhoff pathway) 
10% from pentose phosphate pathway 
 
Methemoglobin Reductase Pathway - correct answer necessary to maintain heme iron in ferrous (Fe2+) state 
Deficiency causes accumulation of methemoglobin, nonfunctional from of Hgb 
 
Leubering Rapaport Shunt - correct answer permits accumulation of 2,3-DPG 
...
SBB study guide #2 questionsWhat is the deferral period for someone who has received a blood transfusion? - correct answer 12 months 
 
Where does the AABB stand on pregnancy and blood donation? - correct answer a woman is deferred if pregnant in the past 6 weeks 
 
What is the deferral period if a potential donor received the varicella zoster vaccine (live attenuated)? - correct answer 4 weeks 
 
What is the deferral period for a whole blood donor who received the yellow fever live vaccine? - c...
SBB study guide questions 
What enzyme may be useful in distinguishing anti-Ge2 from anti-Ge3? - correct answer Papain (Anti-Ge2 will not react) 
 
The beta 1-3 linkage between galactose and N-actylglucosamine is found in: - correct answer Secretions 
 
Which of the following represents the Type II chain? - correct answer Beta 1-4 linkage between galactose and N acetyl glucosamine 
 
Rank the order of decreasing H concentration on RBCs - correct answer 0>A2>B>A2B>A1>A1B 
 
All of ...
SBB STUDY SET 2Which of the following is proper procedure for preparation of platelet concentrates? - correct answer One light spin followed by one hard spin 
 
Irradiation of donor blood is intended to prevent which type of adverse transfusion reaction? - correct answer Transfusion associated Grat vs Host Disease (TA_GVHD) 
 
A unit of whole blood should yield a minimum of... - correct answer 80 IU of Factor VIII and 150 mg of fibrinogen 
 
Which of the following phenotypes will react with an A...
SBB test prep - Clinical Immunohematology and Transfusiondegree of matching for HLA-matched platelets - correct answer Match Grade A: All four antigens identical 
Match Grade B1U: Only three antigens detected in donor, all present in recipient 
Match Grade B2U: Only two antigens detected in donor, both present in recipient 
Match Grade B1X: Three donor antigens identical to recipient, fourth antigen crossreactive with recipient 
Match Grade B2X: Two donor antigens identical to recipient, third &...
SBBChemicals that send signals between cells are - correct answer Cytokines 
 
Antibodies are made by what cells? - correct answer Plasma cells 
 
Where do B cells mature? - correct answer Bone Marrow 
 
Where do T cells mature? - correct answer Thymus 
 
Coating of a cell with antibodies or complement is called? - correct answer Opsonization 
 
CD4 + cells are? - correct answer T helper cells 
 
The specific chemical group that provokes an antibody response - correct answer Epitope 
 
Blood gro...
SBBHep-B Testing - correct answer HBsAg, Anti-HBc, HBV-DNA 
 
Hep-C Testing - correct answer Anti-HCV, HCV RNA 
 
HBsAG - correct answer Appears @ 4 weeks after exposure- drops below detectable level at 24 weeks 
 
HBsAG detectable after 24 weeks - correct answer Chronic Carrier 
 
HBeAG - correct answer envelope Antigen 
 
means that the infection is ACTIVE and REPLICATING 
 
*you are extremely infectious here* 
 
anti-HBc - correct answer appears about 6 weeks after exposure IgM first then ig...
SBBIdentifying information on the donor form should include: - correct answer Date and time of donation 
Name 
Address 
Telephone # 
Gender 
Age or DOB 
A record of reasons for prior deferrals, if any 
 
Donors must be given educational material regarding: - correct answer Infection diseases transmitted by blood transfusion 
Signs and symptoms of AIDS 
Risks of procedure 
Circumstances in which infection disease testing is not performed 
should be given chance to ask questions 
 
Donor qualifica...
Turcan SBB exam review AABB PacketRh inheritence of Rhnull - correct answer Lack LW 
Lack FY5 
 
KEL3 Issues - correct answer KPa 
in cis position may have suppressive effect on other Kell system antigens 
 
Adsorption applications in RBC testing - correct answer Remove autoantibody 
Separate multiple antibodies 
Confirm antigen or antibody specificity 
 
Antilymphocyte Globulin (ALG) - correct answer Made from horse serum 
Interferes with DAT and IAT 
Relation to Lu(a-b-) 
 
PCR and TMA - corre...