Edapt perfusion - Study guides, Class notes & Summaries
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NR507 Advanced Pathophysiology MidTerm Exam Already Graded A+
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Hypersensitivity: Type 1 
Type 1: Allergic reaction, Mediated by IgE, Inflammation due to mast cell degranulation 
 
Local symptoms: 
-itching 
-rash 
Systemic symptoms: 
-wheezing 
Most dangerous = anaphylactic reaction 
systemic response of hypotension, severe bronchoconstriction 
Main treatment: epinephrine reverses the effects 
 
 
 
Hypersensitivity: Type 2 
Type 2: Cytotoxic reaction; tissue specific (ex: thyroid tissue) 
 
Macrophages are the primary effectors cells involved 
 
Can cause ...
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