Lfa 1 integrin Study guides, Class notes & Summaries
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ALL NBME review Questions Answered 100% correct 2023
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ALL NBME review Questions Answered 100% correct 2023 
TRYPTASE MAST CELL 
 
TRYPSIN PANCREAS 
Tryptase Mast Cell Specific 
marker mast cell activation 
type 1 hypersensitvity uriticaria 
angioedema visceral edema hypotension 
 
 
 
Length Constant = Myelination 
Demylination in MS Decreases Length Constant 
 
 
 
A-Delta Fibers 
thin myelinated fibers 
Thin Myelinated Nerve Fibers 
Detect Temperature + Nociceptive 
 
 
 
GTO 1B 
extrafusal fibers 
Series Connection 
Increase Tension transmit via...
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NBME 26 Questions Answered 100% correct 2023
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How can the jejunum be distinguished from the ileum? (5) 
1. inner mucosal folds (plicae circulares) are more prominent, more numerous, and taller --> (this leads to increased mucosal SA and associated feathered appearance after the administration of oral contrast material) 
 
2. larger caliber, thicker muscular walls 
 
3. longer vasa rectae 
 
4. fewer arcades 
 
 
5. the ileum is notable for the presence of Peyer patches and mucosal lymphoid fo...
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LFA-1 integrin 
CD11, cell adhesion molecule that binds ICAM - so the defect is in tight adhesion (PECAM is transmigration). 
 
 
 
DNI vs DNR 
do not intubate (tube), DNR is like atropine, chest compressions. 
 
 
 
Creatine is secreted or absorbed 
Secreted at the PCT. 
 
 
 
proximal convoluted tubule (PCT) 
segment of the nephron between the glomerular capsule and the nephron loop 
 
 
 
What is the arcuate nucleus? 
1 of 4 dopaminergic pathways. Pr...
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NBME 26 Questions Answered 100% correct 2023
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NBME 26 Questions Answered 100% correct 2023 
Absence of the gamma region on SPEP indicates 
immunodeficiency with hypogammaglobulinemia or agammaglobulienmia 
 
 
 
increased left atrial pressure during ventricular systole on the pressure-time graph indicates 
mitral regurgitation, likely from rupture of the chordae tendinae 
 
 
 
Mannitol's effect on serum osmolality 
increases serum osmolality (and in turn, triggers production of ADH) 
 
 
 
hypoventilation is characterized by 
increased Pa...
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USMLE STEP 1 – Pathology Exam 2023 Solved 100%
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Characteristics of Dysplasia - ANSWER-Loss of uniformity of cell size and shape = pleomorphism, 
Loss of tissue orientation, 
Nuclear changes - increase nuclear:cytoplasmic ratio and clumped chromatin 
 
Reversible cell changes to injury - ANSWER-Cellular and mitochondrial swelling due to reduce ATP leading to reduce activity of Na/K and Ca pumps, 
 
Membrane blebbing, 
 
Nuclear chromatin clumping, 
 
Ribosomal / polysomal detachment (reduced protein synthesis). 
 
Irreversible cell changes to ...
![NBME 26 Questions with Full Answers for exam Review](/docpics/5057638/6623add7497a4_5057638_121_171.jpeg)
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NBME 26 Questions with Full Answers for exam Review
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How can the jejunum be distinguished from the ileum? (5) 
1. inner mucosal folds (plicae circulares) are more prominent, more numerous, and taller --> (this leads 
to increased mucosal SA and associated feathered appearance after the administration of oral contrast 
material) 
2. larger caliber, thicker muscular walls 
3. longer vasa rectae 
4. fewer arcades 
5. the ileum is notable for the presence of Peyer patches and mucosal lymphoid follicles 
What is the most likely explanation for the...
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NBME Test
- Exam (elaborations) • 13 pages • 2024
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LFA-1 integrin - Answer*CD11, cell adhesion molecule that binds ICAM - so the defect is in 
tight adhesion (PECAM is transmigration). 
DNI vs DNR - Answer*do not intubate (tube), DNR is like atropine, chest compressions. 
Creatine is secreted or absorbed - Answer*Secreted at the PCT. 
proximal convoluted tubule (PCT) - Answer*segment of the nephron between the glomerular 
capsule and the nephron loop 
What is the arcuate nucleus? - Answer*1 of 4 dopaminergic pathways. Projects to the anterior ...
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