Nonhomologous end joining - Study guides, Class notes & Summaries

USMLE STEP 1- First AidDiseases/Disorders/Deficiencies/Syndromes Exam 2023 (A+) Adenosine deaminase (ADA) deficiency - ANS-An immunodeficiency disorder and one type of SCIDs that is caused by an *inborn error in the metabolism of adenine*. The accumulation of adenine destroys both B and T lymphocytes. Increase in dATP is lymphotoxic Lesch-Nyhan syndrome - ANS-*Defective purine salvage due to absent HGPRT*, which converts hypoxanthine to IMP and guanine to GMP. Results in *excess uric ...

Lesch-Nyhan Syndrome: what causes it and what are manifestations? - ***HGPRT deficiency in purine salvage pathway (this enzyme normally converts hypoxanthine to IMP and guanine to GMP). This deficiency leads to excessive Uric acid production and de novo purine synthesis. It is X linked recessive. Symptoms: hyperuricemia, gout, aggression / self mutilation, mental retardation, dystonia. 2. Treatment for Lesch-Nyhan? - ***Allopurinol / febuxostat second line. Both of these drugs inhibit...

Which statement could be a potential ramification of a defective nucleotide excision repair (NER) pathway? Thymine dimers would persist, decreasing the probability of developing skin cancer. A patient has received a large dose of ionizing radiation at his place of employment. Which scenario is accurate? Double-stranded DNA breaks are being repaired by nonhomologous end joining, without the use of a homologous template. Immediately following transcription, mRNA must be processed b...

BioChem C785 Study Guide PA 2024 Complementary DNA and/or RNA molecules pair with each other by hydrogen bonding during replication, transcription, or translation. Which of the following pairs of molecules are complementary? (Select all that apply) - Answer ️️ -tRNA and mRNA mRNA and template DNA During DNA replication the parent strands ______ and DNA polymerase______. - Answer ️️ - separate, creates the new DNA strands The following sequence is one strand of the DNA that makes u...

WGU C785 Final Exam With All The Correct Answers 2023 What is the basic structure of an amino acid? What do they look like? - amino group (NH2 or NH3), carboxyl group (COO or COOH), alpha carbon (C), and variable group How do you identify the 3 different types of side chains: non-polar/hydrophobic, polar, and charged? - Non-polar/hydrophobic - end with CH or "can't have" water. Polar - end with OH, SH, or NH. Charged - end with a charge what kinds of bonds do each of the 3 different ...

BIOL4374/6374/ BCHS 4313| CELL BIOCHEMISTRY EXAM 2 WITH 100% CORRECT ANSWERS 2024| GRADED A+ Which of the following DNA sequences is not commonly carried on mobile genetic elements? You may choose more than one option. A. transposase gene B. Holliday junction C. recognition site for transposase D. antibiotic resistance gene 2) DNA synthesis begins at: A. the telomeres B. the centromere C. the replication origins D. the CpG islands 3) At a replication fork, both strands of DNA are repl...

Bio 041 Final Exam Practice 40 Questions with Verified Answers Chemical reactions carried out by living systems depend on the ability of some organisms to capture and use atoms from nonliving sources in the environment. The specific subset of these reactions that use nutrients in food to build macromolecules can be described as _____________. a) metabolic. b) catabolic. c) anabolic. d) biosynthetic (question from practice exam 1) - CORRECT ANSWER catabolic In photosystem I, electrons ...

in the organization of DNA into chromosomes, DNA is wrapped around ______ to form nucleosomes. nucleosomes are organized further to form ______ Ans - histones chromatin what would lead to disease due to change in protein structure Ans - interactions within primary protein structure Ans - sequence of amino acids held together by peptide bonds interactions within secondary structure Ans - formation of hydrogen bonds bonds occur between the backbone, it doesn't affect the type of amino ac...

Cancer - ANSWER-Disease caused by abnormal and uncontrolled cell proliferation, followed by invasion and colonization of body sites normally reserved for other cells DNA Ligase - ANSWER-Enzyme that reseals nicks that occur in the backbone of a DNA molecule (in the lab, can be used to join together two DNA fragments) DNA Polymerase - ANSWER-Makes DNA DNA Repair - ANSWER-Collective term used for the enzymatic processes that correct deleterious changes affecting the continuity or sequence ...

TOPIC: BIOCHEMISTRY - MOLECULAR / "CHROMATIN STRUCTURE" WHAT BINDS TO THE NUCLEOSOME AND TO LINKER DNA TO STABILIZE CHROMATIN FIBER? - ANSWER-H1 TOPIC: BIOCHEMISTRY - MOLECULAR / "CHROMATIN STRUCTURE PHOSPHATE GIVES DNA WHAT CHARGE? - ANSWER-NEGATIVE TOPIC: BIOCHEMISTRY - MOLECULAR / "CHROMATIN STRUCTURE WHAT GIVES HISTONES A POSITIVE CHARGE? - ANSWER-LYSINE AND ARGININE TOPIC: BIOCHEMISTRY - MOLECULAR / "CHROMATIN STRUCTURE WHEN DOES DNA CONDENSE TO FORM CHROSOMES? - A...