Pc707 mod 1 - Study guides, Class notes & Summaries

Phase 1 - Evaluate safety, 40-50 healthy volunteers Phase 2 - Evaluate efficacy, 10-100 patients Phase 3 - Statistical analysis of safety & efficacy, double blinded RCT Phase 4 - post marketing surveillance Absorption - The movement of a drug from the site of administration into circulation Bioavailability - Amount of ACTIVE drug that reaches systemic circulation Distribution - The movement of a drug form systemic circulation to the site of action Protein binding - Drugs are inactive when...

PC707 Mod 8 Exam Questions and Answers Affrezza (inhaled rapid acting insulin) - Answer ️️ -risk of bronchospasm in patients with chronic lung disease. Metformin (Biguanide) - Answer ️️ -severe metabolic acidosis can occur with increase accumulation of [insert drug name]. Highest risk with renal impairment. Actos (thiazolidinediones) - Answer ️️ -can cause or exacerbate CHF in some patients. After initiation [insert drug name], and after dose increases, observe patients careful...

PC707 Mod 8 Exam Questions and Answers Affrezza (inhaled rapid acting insulin) - Answer ️️ -risk of bronchospasm in patients with chronic lung disease. Metformin (Biguanide) - Answer ️️ -severe metabolic acidosis can occur with increase accumulation of [insert drug name]. Highest risk with renal impairment. Actos (thiazolidinediones) - Answer ️️ -can cause or exacerbate CHF in some patients. After initiation [insert drug name], and after dose increases, observe patients careful...

PC707 Mod 8 Exam Questions and Answers Affrezza (inhaled rapid acting insulin) - Answer ️️ -risk of bronchospasm in patients with chronic lung disease. Metformin (Biguanide) - Answer ️️ -severe metabolic acidosis can occur with increase accumulation of [insert drug name]. Highest risk with renal impairment. Actos (thiazolidinediones) - Answer ️️ -can cause or exacerbate CHF in some patients. After initiation [insert drug name], and after dose increases, observe patients careful...

Phase 1 - Answer-Evaluate safety, 40-50 healthy volunteers Phase 2 - Answer-Evaluate efficacy, 10-100 patients Phase 3 - Answer-Statistical analysis of safety & efficacy, double blinded RCT Phase 4 - Answer-post marketing surveillance Absorption - Answer-The movement of a drug from the site of administration into circulation Bioavailability - Answer-Amount of ACTIVE drug that reaches systemic circulation Distribution - Answer-The movement of a drug form systemic circulation to the site of ...