Cytochrome p450 Study guides, Class notes & Summaries

NURS 6630 Midterm Exam Test Bank Questions and Answers 100%Correct NEW 2023. Question 1 1 out of 1 points A noncompliant patient states, “Why do you want me to put this poison in my body?” Identify the best response made by the psychiatric-mental health nurse practitioner (PMHNP). Answer: C. “Most medications that work in the brain will result in restoring an imbalance of one or more neurotransmitters that your body already produces helping to alleviate your symptoms .” Question...

NR 546 Midterm Exam 2023/2024 Questions AND Answers Update A+ What should the PMHNP consider when prescribing chemical restraints? - Answer-- allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are the PMHNP and other staff liable if the client has an allergic reaction or adverse side effects to the drugs used for chemical restraint? - Answer-No. The client has been court-...

During what trimester is a pregnant woman most at risk for adverse drug reactions with potential long term consequences? 1st trimester (fetus most at risk d/t rapid growth) What is BEERS criteria? Recommendations of medications inappropriate for elderly (65 and older), prescriber ultimately decides What is the CYP450 (cytochrome P450) liver enzyme system where medications are metabolized, can either be inducers or inhibitors and create drug-drug interactions CYP450 inducers Speed up metabo...

NR565 ADVANCED PHARMACOLOGY FUNDAMENTALS EXAM REVIEW QUESTIONS AND ANSWERS, GRADED A+ Pharmacokinetics - -The process by which drugs are absorbed, distributed within the body, metabolized, and excreted. Pharmacodynamics - -The study of what the drug does to the body Factors Affecting Drug Absorption - -Rate of dissolution Surface area Blood flow Lipid solubility pH partitioning Factors Affecting Drug Distribution - -Blood flow to tissues Ability to exit the vascular system Blood-bra...

Most cytochrome P450 enzymes alter the activity of drugs by: correct answers Cytochrome P450 acts as monooxygenases, where an oxygen atom is inserted into a substrate (the drug of interest), thereby resulting in the oxidation of the substrate. During phosphorylation of STAT5b proteins,phosphate groups are exchanged for what atoms on tyrosine residues? correct answers The passage notes that JAK2 is a tyrosine kinase. Tyrosine has a nucleophilic hydroxyl group that attacks the terminal phosphat...

Midterm Exam: NR546/ NR 546 Psychopharmacology for the Psychiatric-Mental Health Nurse Practitioner MIDTERM Exam Review | Complete Guide Questions and Verified Answers| 2023/ 2024 Updated!! – Chamberlain What should the PMHNP consider when prescribing chemical restraints? - ANSWER -allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are...

NRNP 6566 WK1-5 Midterm Questions and Answers 100% Pass **What is the Cytochrome P450 system responsible for?** A) Breaking down carbohydrates B) Metabolizing medications C) Synthesizing proteins D) Producing energy ** Answer: B) Metabolizing medications** **What do inhibitors of the Cytochrome P450 system do?** A) Enhance metabolic activity B) Have no effect on enzyme function C) Block metabolic activity from one or more CYP450 enzymes D) Reduce enzyme synthesis ** Answer...

First Pass Metabolism CORRECT ANSWER GI Tract ---> Portal Circulation ---> Liver --->Metabolized ---> Systemic Circulation 1st pass metabolism lowers the amount of drug available. If high first-pass effect, mostly becomes inactivated and cannot be used, these meds cannot be given orally. Example: Insulin Drug Metabolism CORRECT ANSWER The most active organ is the LIVER (Cytochrome P450 enzyme system) Others are Kidneys, GI Tract, Lungs Coumadin and Bactrim CORRECT ANSW...

Advanced Pharmacology- FNP Exam Questions with Correct Answers 100% Verified 2024/2025 True or False: Children metabolize drugs faster than adults. - Correct Answer True which are easier to excrete: water soluble drugs or lipid soluble drugs? - Correct Answer Water soluble What are the cytochrome p450 inducers? (CRAPGPS) - Correct Answer Carbamazapine Rifampin Alcohol Phenytoin Griseofulvin Phenobarbital Sulfonylureas and St. Johns Wort what do CYP450 inducers do? - Correct An...

Pharmacokinetics (Ans- the study of what happens to a drug from the time of administration until the parent drug and all metabolites leave the body Pharmacokinetics concepts (Ans- absorption distribution metabolism excretion Flockhart Table (Ans- drug interactions that are mediated by cytochrome P450 enzymes comprehensive list of drugs and the interactions related to the cytochrome P450 system client factors that impact the effect of psychotropic medications (Ans- -age...