Bace 2023 - Study guides, Class notes & Summaries

Clinical Trial- Phase 1 - - Tests drug in healthy individuals - Tests for safety, dosage, and side effects Clinical Trial- Phase 2 - - Tests on larger group of effected individuals - Tests for efficacy and side effects Clinical Trial-Phase 3 - - Tests on new and wider demographic - Tests for long term effectiveness and comparisons with other medications Clinical Trial- FDA Approval - Treatment determined effective and safe for public use Clinical Trial- Phase 4 - - Cont...

NaCl is a: -nonpolar covalent -ionic -polar covalent - ionic H2O is a: -nonpolar covalent -ionic -polar covalent - polar covalent CH4 is a: -nonpolar covalent -ionic -polar covalent - nonpolar covalent What should be used to calculate the amount of compound required to make a solution? - molecular weight What is an example of a carbohydrate and its associated functions? - Example is cellulose. Functions are energy storage, receptors, structure of plant cell...

cell theory states - All life forms are made from one or more cells. Cells only arise from pre-existing cells. The cell is the smallest form of life. E.coli is an example of a eukaryote - false Quality Assurance - ensure that all products meet standards of quality in manufacturing process reasearch and development (R AND D) - identify candidate biopharmaceutical drugs Manufacturing - make commercial quantities of biopharmaceutical drug Which structure regulates the flow of molecul...

The invention of the thermal cycler The use of reverse transcriptase from single-stranded RNA The use of fluorescently-tagged probes for real-time quantitation of PCR products - SIgnificant Advances in PCR include the structure of DNA was described, as well as its method of replication - What happened in the 1950s? the isolation of restriction enzymes - The advent of recombinant DNA technology began with what? it allowed us to manipulate DNA - What did the advent of recombinant DNA t...

safety shower location - toxic/poisonous materials - biohazard - hot surface - don't drink the water - defibrillator or AED location - eye protection required - harmful or irritant - eyewash station - gloves required - fire extinguisher location - first aid station - protective clothing required - corrosive - radioactivity - oxidizer - analytical balance - measure mass autoclave - sterilizes med...

What is an example of a product easily found in nature? - Antibiotic In a biotechnology lab, what is tap water is best used for? - Washing glassware. What is the order of amino acids on a polypeptide chain encoded by? - mRNA How do DNA molecules vary from one species to another? - Number of genes and non-coding regions. What is agar? - Solid media on which bacteria grow. What part of an amino acid differs from one to the other? - R group How can colorless proteins be monitored ...

4.651 x 10^4 written in expanded form is - 46,510 What is 5.78 x 3.13, rounded to the correct number of significant digits? - 18.1 What is 4.202 x 0.806, rounded to the correct number of significant digits? - 3.39 How many grams is 2.6 kg? - 2600 How many milliliters is 0.725L? Group of answer choices - 725 Your supervisor provides you with a 1.0 mg/mL solution of Bovine Serum Albumin (BSA), and asks you to make a 5-step 2-fold serial dilution. What would be the dilution factor a...

All life forms are made from one or more cells. Cells only arise from pre-existing cells. The cell is the smallest form of life. - What are the three components the cell theory? Prokaryotes are unable to properly fold and assemble more complicated eukaryotic proteins. - What is a disadvantage to using prokaryotes in the production of biopharmaceuticals ? Plasma membrane - regulates the flow of molecules into and out of the cell 37 C - What is the temperature for the maximum gr...

running protein gels - vertical gel electrophoresis DNA ligase - joining pieces of DNA running DNA gels - horizontal gel electrophoresis restriction enzymes - digesting DNA DNA polymerase - synthesizes DNA by adding nucleotides one by one DNA helicase - separates DNA into two strands how does immune checkpoint therapy work? - immune checkpoint therapies can stop the immune system's response traditional treatments for cancer such as radiation and chemotherapy w...

what is not considered a significant advance in PCR methodology - the use of agarose gel electrophoresis to visualize amplified products describe DNA ligase - joining pieces of DNA together describe heat stable DNA polymerase - performing PCR reactions describe protease - degrading protein describe restriction enzymes - digesting DNA what is a negative outcome of growing or consuming genetically modified food crops? - decrease genetic diversity bioethics is best des...