Bmtcn chapter 1 - Study guides, Class notes & Summaries

BMTCN Chapter 5: Graft-versus-Host Disease Already Passed T.R. is a 28-year-old woman with acute myeloid leukemia in her second complete remission who is admitted for a matched unrelated allogeneic stem cell transplantation. Her conditioning regimen is as follows: Myeloablation (busulfan/cyclophosphamide) and immunosuppression with tacrolimus and methotrexate (5 mg/m2 on days +1, +3, +6, and +11). She did not receive methotrexate on day +11 because of severe mucositis. Her transplant course w...

BMTCN Chapter 1red marrow - what does it make, and where? - correct answer produces hematopoietic stem cells that create RBC, WBC, platelets, found in long, flat bones yellow marrow - what does it make, and where? - correct answer produces stromal stem cells for fat, cartilage, nad bone, found in long bones where are hematopoietic cells made in adults vs children? - correct answer long bones in childhood, axial skeleton in adulthood myeloid cells mature into: (4) - correct answer megaka...

BMTCN REVIEW CHAPTER 1-BASIC CONCEPTS AND INDICATIONS FOR TRANSPLANTATION TEST QUESTIONS AND ANSWERS

Which of the following is an example of a myeloid cell? A. Thymus-derived cells (T cells) B. Bone marrow-derived cells (B cells) C. Monocytes D. Natural killer cells - ANSWER-C. Monocytes Several factors affect immune reconstitution following hematopoietic stem cell transplantation (HSCT). These include all of the following EXCEPT: A. Recipient's response to conditioning regimen B. Viral infections C. Chronic graft-versus-host disease D. Longevity of mature lymphocytes present at the ...

BMTCN REVIEW CHAPTER 1-BASIC CONCEPTS AND INDICATIONS FOR TRANSPLANTATION TEST QUESTIONS AND ANSWERS

BMTCN Chapter 3 - Pretransplant Issues S.J. is about to undergo leukapheresis in preparation for an autologous transplant. The nurse informs her that she may experience tingling in her lips and extremities during the procedure. Which statement best explains this symptom? A. Numbness and tingling are signs of a hypersensitivity reaction to the medications commonly used for mobilization. B. Paresthesia of the mouth and extremities may occur during leukapheresis because the sodium citrate added ...

Goal of Transplant - ANSWER--Cure disease -Increase disease free survival Hematopoiesis - ANSWER--Regulation, production and development of blood cells -Pluripotent Stem cells -Progenitor Stem Cells. -Myeloid and lymphoid lineage Myeloid progenitor cells mature into: - ANSWER-Megakaryocytes (platelets) Erythrocytes Mast cells Myeloblasts Lymphoid progenitor cells mature into: - ANSWER-Small lymphocytes (B cells/T cells) Natural Killer Cells B cells - ANSWER--Develop in the bone mar...

Two types of marrow - ANSWER-red and yellow red marrow - ANSWER-thick, blood like material found in flat bones and the ends of long bones; location of blood cell formation yellow marrow - ANSWER-soft, fatty material found in the medullary cavity of long bones Hematopoietic location through lifespan - ANSWER-long bones during childhood; axial skeleton in adulthood Cytokines - ANSWER--small proteins important in cell signaling -immunomodulating agents; may up or down regulate the immune sy...

Two types of marrow - ANSWER-red and yellow red marrow - ANSWER-thick, blood like material found in flat bones and the ends of long bones; location of blood cell formation yellow marrow - ANSWER-soft, fatty material found in the medullary cavity of long bones Hematopoietic location through lifespan - ANSWER-long bones during childhood; axial skeleton in adulthood Cytokines - ANSWER--small proteins important in cell signaling -immunomodulating agents; may up or down regulate the immune sy...

Goal of Transplant -Cure disease -Increase disease free survival Hematopoiesis -Regulation, production and development of blood cells -Pluripotent Stem cells -Progenitor Stem Cells. -Myeloid and lymphoid lineage Myeloid progenitor cells mature into: Megakaryocytes (platelets) Erythrocytes Mast cells Myeloblasts Lymphoid progenitor cells mature into: Small lymphocytes (B cells/T cells) Natural Killer Cells B cells -Develop in the bone marrow -Differentiat...