Nros 310 - Study guides, Class notes & Summaries

Describe what would happen to the nuclear export process if RAN GAP was present on both sides of nuclear membrane - Answer Ran would be in the GDP form inside the nucleus. Nuclear export would cease because exportin would not be able to bind RAN-GTP and thus not bind and export cargo. You have identified a sequence that you believe acts as a nuclear localization signal. Describe an experiment that you could do (and the results of that experiment) to show: That your sequence is necessary...

NROS 310 Final Exam 2023 with 100% correct answers

NROS 310 Exam 1 questions with correct answers

What are the three main components of the cytoskeleton and what are their main functions? - ANSWER Microfilaments (actin): sense the environment and direct movement Intermediate Filaments: maintain cell shape/structure, anchor organelles Microtubules: for transport What are the main similarities and differences between the three components of the cytoskeleton? - ANSWER Similarities: -important for cytoskeletal structure -charged ends; form a highway for motor protein Differences: ...

What are the main organs affected by cystic fibrosis? - Lungs, any organ that has epithelial cells, mucus, and secretory system which requires regulation of that mucus Describe the main function of the CFTR protein and how it is regulated. - responsible for regulating the proper flow of chloride and sodium (a component of salt) in and out of the cell membranes in the lungs and other organs. It is regulated by its cytosolic domains: two nucleotide binding domains (NBDs) and a regulatory (R) ...

What are the three main components of the cytoskeleton and what are their main functions? - Microfilaments: made of actin; determines the shape of cell surface and is important for the movement of the cell Microtubules: made of alpha and beta dimers ; act as tracks for vesicles and other properties to move about the cell with motor proteins Intermediate filaments: made of various proteins + rope-like fibers; provide mechanical strength The actin filament and microtubules carry stuff by "w...

What are the three main components of the cytoskeleton and what are their main functions? - ANSWER Microfilaments (actin): sense the environment and direct movement Intermediate Filaments: maintain cell shape/structure, anchor organelles Microtubules: for transport What are the main similarities and differences between the three components of the cytoskeleton? - ANSWER Similarities: -important for cytoskeletal structure -charged ends; form a highway for motor protein Differences: ...

Why are there motor proteins associated with both actin filaments and microtubules but not intermediate filaments? - ANSWER Actin filaments and microtubules are highly polarized, therefore allowing motor proteins to form associations with them. Intermediate filaments are unpolarized and do not bind nucleotides such as ATP, leading to lack of motor protein associations (which are ATP driven). How does the hydrolysis of ATP cause myosin to move along the actin filament? - ANSWER ATP hydrolysis ...

Describe the function of the following cellular structures or organelles: nucleus, endoplasmic reticulum, ribosomes, peroxisomes, lysosomes, mitochondria, golgi apparatus, plasma membrane. - Answer . If all cells in an organism have the same genomic DNA, what makes a liver cell different than a neuron? - Answer translation of different proteins what DNA gets expressed as protein-protein interactions What are the nucleotides that make up DNA and how do they interact? What are the bene...