P450 system - Study guides, Class notes & Summaries

1. Pharmacokinetics ANS The process by which drugs are absorbed, distributed within the body, metabolized, and excreted. 2. Pharmacodynamics ANS The study of what the drug does to the body 3. Factors Affecting Drug Absorption ANS Rate of dissolution Surface area Blood flow Lipid solubility pH partitioning 4. Factors Affecting Drug Distribution ANS Blood flow to tissues Ability to exit the vascular system Blood-brain barrier Protein-binding capacity 5. Xenobiotics ANS substances that a...

CU NR 546 Questions and Answers with Complete Solutions How can genetic testing aid the PMHNP in developing a personalized treatment plan for patients? A. By identifying specific genetic markers for mental health disorders B. By providing information on how clients may respond to certain psychotropic medications and break down and metabolize medications based on the cytochrome P450 system C. By identifying genetic links to certain medications D. By determining the client's ancestr...

NR 565-ADVANCED PHARMACOLOY MIDTERM WITH QUESTIONS AND WELL VERIFIED ANSWERS [GRADED A+] ACTUAL EXAM 100%] During what trimester is a pregnant woman most at risk for adverse drug reactions with potential long term consequences? - ANS---1st trimester (fetus most at risk d/t rapid growth) What is BEERS criteria? - ANS---Recommendations of medications inappropriate for elderly (65 and older), prescriber ultimately decides CYP450 inducers - ANS---Speed up metabolism of drugs (drug is cleared faster...

Pharmacology NU 578 - Unit 1 &2 Exam Questions and Answers (Verified Answers). Full term - ANSWER 36-40 weeks gestation Ganglionic blocking agents - ANSWER Interrupt impulse transmission through ganglia of the autonomic nervous system. They do this by competing with Ach for binding to nicotinic receptors in autonomic ganglia. Generic name - ANSWER Assigned by US Adopted Names Council. -each drug has only ONE -aka nonproprietary name or US Adopted Name Glomerular filtration - ANSWER Moves ...

NR546 Midterm Exam Questions and Answers Already Graded A What essential factors should the PMHNP consider when administering chemical restraints to a patient? A. The patient's age and medical history B. Allergy status, prior medication history for adverse drug reactions, and state regulations regarding chemical restraints C. The patient's weight and height D. The patient's social status and insurance coverage **Answer:** B. Allergy status, prior medication history for adver...

Prodrug - Answer An inactive drug dosage form that is converted to an active metabolite by various biochemical reactions once it is inside the body. -Cytochrome P450 -Ex. Aspirin, psilocybin, heroin Bioavailability - Answer the rate at and the extent to which a nutrient is absorbed and used -Affected by route of administration and drug dosage -Drug clearance (rate drug leaves circulation) -Steady state concentration -Affected by chemical stability, solubility, and first pass Steady stat...

What should the PMHNP consider when prescribing chemical restraints? - -allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are the PMHNP and other staff liable if the client has an allergic reaction or adverse side effects to the drugs used for chemical restraint? - No. The client has been court-ordered to take the prescribed medications and the standing order for chemical re...

How does reviewing the genetic makeup of a client help guide the PMHNP in selecting medication for clients? ANS Genetic testing can assist by providing moreinformation on how clients may respond to certain psychotropic medications, as well as providing information on how a client may break down and metabolize medications based on the cytochrome P450 system. There may be an environmental exposure that turned a gene "on" that should havebeen "off" for one twin to develop schizophrenia an...

TEST BANK FOR EDMUNDS PHARMACOLOGY FOR THE PRIMARY CARE PROVIDER 5TH EDITION BY CONSTANCE G VISOVSKY | ALL CHAPTERS . Which of the following has influenced an emphasis on primary care education in medical schools? a. Changes in Medicare reimbursement methods recommended in 1992 b. Competition from nonphysicians desiring to meet primary care shortages c. The need for monopolistic control in the marketplace of primary outpatient care d. The recognition that nonphysicians have variable suc...

NRNP 6566 Midterm Study Guide 2024 with Complete Solutions. Week 1 1. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as for hormon...