Bmb 401 exam 3 msu - Study guides, Class notes & Summaries
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BMB 401 Exam 3 - MSU Test With Complete Solution
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BMB 401 Exam 3 - MSU Test With Complete Solution...
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BMB 401 Exam 3 - MSU Test With Complete Solution 2024
- Exam (elaborations) • 12 pages • 2024
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BMB 401 Exam 3 - MSU Test With Complete Solution 2024
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BMB 401 Exam 3 - MSU WITH 100% VERIFIED SOLUTIONS 2023
- Exam (elaborations) • 9 pages • 2023
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TCA cycle - Step 1, Oxidative Decarboxylation 
Oxaloacetate + Acetyl CoA + H2O -> Citrate + CoA 
Enzyme: Citrate synthase 
Driven by CoA hydrolysis 
 
 
 
High Citrate Levels Indicate 
well fed state 
1. intermediate in TCA cycle (mitochondria) 
2. activator of fatty acid synthesis (cytoplasm) 
3. precursor of cytoplasmic acetyl CoA (cytoplasm) 
4. inhibitor of PFK1 (cytoplasm) 
 
 
 
Regulation of Citrate Synthase 
Major point of regulation 
Negative - ATP, NADH, Succinyl CoA 
 
 
 
TCA cycl...
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