Bme 347 - Study guides, Class notes & Summaries

Why develop regenerative engineering technologies - To optimize naturally occurring regenerative mechanisms what are 2 problems with naturally occurring regenerative mechanisms - Timing: cell regen takes 3-5 days effectiveness: level of regen (ex. too much fibroblast regen/not enough cardiomyocyte regen) What is atherosclerosis? - when a branch of the coronary artery becomes blocked by an atheroma (buildup of plaque/leuokcytes/SMCs/endothelial cells) embolus - piece of atheroma that de...

why does regeneration happen - Injury/insults (physical factors, chemical factors, biological factors) physical factors that could happen to a cell - temperature, radiation, shear stress chemical factors that could happen to a cell - toxins, signaling molecules being present/absent biological factors that could happen to a cell - ROS, oxidants, O2- cause DNA damage what is regenerative engineering - discipline to understand natural regenerative process in injury and disorders to deve...