Boxed warning of plavix Study guides, Class notes & Summaries

Aspirin- MOA Binds irreversibly to cyclooxyrgenase-1 and 2 (COX 1 and 2) Decrease prostaglandin and thromboxane A2 production Plavix (clopidogrel) -MOA Produg- irreversibly inhibits P2Y12 ADP-mediated platelet activation and aggregation Boxed warning of Plavix conversion to active metabolite require (CYP 450 2C19) Poor metabolizers - higher CV events Plavix- avoid to take with what 2c19 inhibitors (omeprazole, esomeprazole) increased bleed

Aspirin- MOA correct answers Binds irreversibly to cyclooxyrgenase-1 and 2 (COX 1 and 2) Decrease prostaglandin and thromboxane A2 production Plavix (clopidogrel) -MOA correct answers Produg- irreversibly inhibits P2Y12 ADP-mediated platelet activation and aggregation Boxed warning of Plavix correct answers conversion to active metabolite require (CYP 450 2C19) Poor metabolizers - higher CV events Plavix- avoid to take with what correct answers 2c19 inhibitors (omeprazole, esomepraz...

Aspirin- MOA - Answer Binds irreversibly to cyclooxyrgenase-1 and 2 (COX 1 and 2) Decrease prostaglandin and thromboxane A2 production Plavix (clopidogrel) -MOA - Answer Produg- irreversibly inhibits P2Y12 ADP-mediated platelet activation and aggregation Boxed warning of Plavix - Answer conversion to active metabolite require (CYP 450 2C19) Poor metabolizers - higher CV events Plavix- avoid to take with what - Answer 2c19 inhibitors (omeprazole, esomeprazole) increased bleed pos...

Aspirin- MOA correct answers Binds irreversibly to cyclooxyrgenase-1 and 2 (COX 1 and 2) Decrease prostaglandin and thromboxane A2 production Plavix (clopidogrel) -MOA correct answers Produg- irreversibly inhibits P2Y12 ADP-mediated platelet activation and aggregation Boxed warning of Plavix correct answers conversion to active metabolite require (CYP 450 2C19) Poor metabolizers - higher CV events Plavix- avoid to take with what correct answers 2c19 inhibitors (omeprazole, esomepraz...

Aspirin- MOA - ANSWER-Binds irreversibly to cyclooxyrgenase-1 and 2 (COX 1 and 2) Decrease prostaglandin and thromboxane A2 production Plavix (clopidogrel) -MOA - ANSWER-Produg- irreversibly inhibits P2Y12 ADP-mediated platelet activation and aggregation Boxed warning of Plavix - ANSWER-conversion to active metabolite require (CYP 450 2C19) Poor metabolizers - higher CV events Plavix- avoid to take with what - ANSWER-2c19 inhibitors (omeprazole, esomeprazole) increased bleed pos...

Aspirin- MOA correct answers Binds irreversibly to cyclooxyrgenase-1 and 2 (COX 1 and 2) Decrease prostaglandin and thromboxane A2 production Plavix (clopidogrel) -MOA correct answers Produg- irreversibly inhibits P2Y12 ADP-mediated platelet activation and aggregation Boxed warning of Plavix correct answers conversion to active metabolite require (CYP 450 2C19) Poor metabolizers - higher CV events Plavix- avoid to take with what correct answers 2c19 inhibitors (omeprazole, esomepraz...

Aspirin- MOA Binds irreversibly to cyclooxyrgenase-1 and 2 (COX 1 and 2) Decrease prostaglandin and thromboxane A2 production Plavix (clopidogrel) -MOA Produg- irreversibly inhibits P2Y12 ADP-mediated platelet activation and aggregation Boxed warning of Plavix conversion to active metabolite require (CYP 450 2C19) Poor metabolizers - higher CV events Plavix- avoid to take with what 2c19 inhibitors (omeprazole, esomeprazole) increased blee