Calcineurin inhibitors - Study guides, Class notes & Summaries

1. The nurse works with a number of clients who require immunosuppressive treatment of autoimmune diseases. What classes of drugs would the nurse expect health care providers to order? Select all that apply. A. Corticosteroids B. Calcineurin inhibitors C. Sodium channel antagonists D. Biologics E. Antibiotics F. Diuretics Answer: A, B, D Rationale: Drugs used to suppress immunity include corticosteroids, calcineurin inhibitors, mTOR inhibitors, IMDH inhibitors, biologics, and monoclon...

Diabetic skin manifestations are called? acanthosis nigricans Why do we give prostaglandins in HF, for kids? To keep the patent ductus arteriosus open until surgery What are nontender small erythematous lesions (macular, papular, or nodular) on the palms associated with infective endocarditis? Janeway Lesions What is Desferal used for? Beta Thalassemia (drug that chronically-transfused pts use to remove excess Iron from their bodies. Iron overload is therefore the leading cause of death a...

Exam 4 (Organ Procurement & Transplant: Lecture Notes), 178 Questions And Correct Answers, With Complete Solution 2024. A single donor can provide up to ____ life-saving organs 8 Can you name the four most commonly transplanted organs? (start the list with the most common) 1. kidneys 2. liver 3. heart 4. lung What is a VCA/CTA? What does this stand for? VCA = vascular composite allograft CTA = composite tissue allograft these are the same thing, basically mean (any) two or more ti...

COMLEX II High Yield Questions and Answers Already Passed _______ is a potential life-threatening complication of central line placement: sudden-onset dyspnea with the presence of a "mill wheel" murmur on PE Venous air embolism -->acute cerebral ischemia if the air passes through a patent foramen ovale ____________ is a complication of choledocholithiasis and should be treated with ____________ ascending cholangitis IV Abs, IV fluids, ERCP w/ sphincterotomy/stone removal or bil...

CCTC Transplant pharmacology Exam 2024 Questions and Answers. Calcineurin inhibitors - Answer Cyclosporine or Sandimmune (Neoral, Gengraf) & Tacrolimus or hecoria (Prograf) MOA of Tacrolimus (Prograf) - Answer binds to fkbp12 to inhibit interleukin 2 production & release. Which inhibits cytotoxic T cells. MOA of Cyclosporine (Neoral, Gengraf) - Answer Binds to cyclophylin to inhibit interleukin 2 production & release. Which inhibits cytotoxic T cells. side effects of tacrolimus - Answer ...

CCTC Transplant pharmacology Exam 2024 Questions and Answers. Calcineurin inhibitors - Answer Cyclosporine or Sandimmune (Neoral, Gengraf) & Tacrolimus or hecoria (Prograf) MOA of Tacrolimus (Prograf) - Answer binds to fkbp12 to inhibit interleukin 2 production & release. Which inhibits cytotoxic T cells. MOA of Cyclosporine (Neoral, Gengraf) - Answer Binds to cyclophylin to inhibit interleukin 2 production & release. Which inhibits cytotoxic T cells. side effects of tacrolimus - Answer ...

CCTC Transplant pharmacology Exam 2024 Questions and Answers. Calcineurin inhibitors - Answer Cyclosporine or Sandimmune (Neoral, Gengraf) & Tacrolimus or hecoria (Prograf) MOA of Tacrolimus (Prograf) - Answer binds to fkbp12 to inhibit interleukin 2 production & release. Which inhibits cytotoxic T cells. MOA of Cyclosporine (Neoral, Gengraf) - Answer Binds to cyclophylin to inhibit interleukin 2 production & release. Which inhibits cytotoxic T cells. side effects of tacrolimus - Answer ...

Organ rejection that occurs minutes to hours after transplantation due graft specific cytotoxic antibodies is - hyperacute rejection if a patient is seropositive prior to the transplant or after receiving a seropositive organ or blood transfusion that patients is at risk for developing what infection - cytomegalovirus infection posttransplant patients are at increased risk for malignancies secondary to - persistent viral infections and prolonged immunosuppressant therapy risk f...

NURS549 Final Exam Study Guide Solutions 2 Monoclonal immunosuppressive Antibody Drugs - Ans:-Daclizumab(zenapax)- Reduces activated T- cell numbers and activities by binding to interlukin Muromonab(orthoclone)-Binds to CD3 receptors on T cells and disrupts function. Depletes circulating T cells Monoclonal Antibody drug MOA - Ans:-Clinical application is in TARGETING T-CELLS AS ANTIGENS, tagging them for attack, disrupting T-Cell ( Cell Mediated Immunity ) function and ultimately providin...

half-life - the time required for the amount of drug in the body to decrease one half of the peak level first-pass effect - a phenomenon of oral drug metabolism whereby the concentration of a drug is greatly reduced in the liver before it reaches the systemic circulation; drugs given IV bypass this effect bacteriostatic vs. bactericidal - bacteriostatic inhibits the proliferation of bacteria while bactericidal kills bacteria cross-sensitivity - a sensitivity reaction to a drug that predisp...