Ebme 306 stuvia 2024 - Study guides, Class notes & Summaries

What class device would a 'Drug Eluting Arterial Stent' be classified as? A) Class II device B) Class I device C) Class III device D) Class IV device - ANSWERD) Class IV device A suitable staining agent for a blood smear is: A) Gram's Stain B) Masson's Trichrome Stain C) H&E Stain D) Wright's Stain - ANSWERD) Wright's Stain In the context of biomaterials, the FDA regulates: A) Metals and Polymers B) Ceramics and Polymers C) Any material invented in a lab and test in vitro ...

Define biomaterial - ANSWERAny substance, other than a drug, or combination of substances, synthesized or natural in origin which can be used for any period of time, as a whole or part of the system, which treats, augments, or replaces any tissue organ or function of the body. (is in contact with living tissue) (contact lens vs eye glasses) OR a synthetic or natural material that is used to replace part of a living system or to function in intimate contact with living tissue What is biocomp...

Biomedical Device - ANSWERAny instrument, appliance, machine, material or other related article intended by the manufacturer to be used for human beings for the purpose of diagnosis, prevention, monitoring, treatment, or alleviation of disease or injury. Class 1 Medical Devices - ANSWERLow risk, not intended to support or sustain life or cause unreasonable illness or injury Do not need to be reviewed by the FDA Ex: tongue depressors, elastic bandages Class 2 Medical Devices - ANSWERDevic...

Degree of polymerization: - ANSWERnumber of structural units in the chain Homopolymer - ANSWERpolymer structure contains same repeating unit Heteropolymer - ANSWERpolymer structure contains different repeating units Copolymer - ANSWERa polymer derived from more than one species of monomer All heteropolymers are copolymers but the reverse is not true: JUSTIFY!! - ANSWERB/c copolymers can still have single repeating unit (like PET, PC) Number average molecular weight (Mn) - ANSWERMn...

Given immunocytochemistry technique List: 1. Advantages 2. Disadvantages 3. Applications - ANSWER Immunohistochemistry and immunocytochemistry - ANSWERAdvantages: Specific localisation of antigens in situ. Staining lasts for years. Relatively inexpensive- no specialised equipment required. Disadvantages: Not suitable for light impenetrable materials. Qualitative, and subjective without computer analysis. Application: Commonly used for the examination of pathological samples e....

Class 1 - ANSWERLow risk devices that don't require FDA approval before marketing Ex: Clamps or Bandaids Class 2 - ANSWERMore risk than Class 1 but not life sustaining Ex: surgical needles Class 3 - ANSWERLife sustaining Ex: heart valve Combination Product - ANSWERusually drug+device Ex: condom with spermicide Hemotoxylin and Eosin Stain - ANSWERused for general morphology, stains pink and blue Collagen Stain - ANSWERMasson's Trichrome (blue) to see live cells Bacteria Stain ...

Immunity - ANSWERResponse to foreign substances, part of chronic inflammatory response Innate Immunity - ANSWERrapid but limited, nonspecific, present at birth, includes complement system Adaptive immunity - ANSWERslow but vast, acquired through exposure, specific Non-immune Defenses - ANSWERskin, mucus (respiratory, urinary), HCl (stomach) lactic acid (vaginal) Major Lymph Organs - ANSWERlymph nodes, spleen, thymus, tonsils Role of the Thymus - ANSWEREducates T cells (differentia...

Medical Devices - ANSWERanything used for humans for diagnostics, prevention, monitoring, treatment, disinfectant, birth control, or life support Etiology - ANSWERcause of disease Pathology - ANSWERstudy to find cause, origin and nature of disease Biocompatibility - ANSWERability of a material to perform with an appropriate host response in a specific application Pathogenesis - ANSWERsequence of events that lead to structural or functional abnormalities How immunostaining works - ...

What are the 3 main classes of biomaterials? - ANSWERMetals, ceramics, and polymers Name 4 natural biomaterials - ANSWER1. Proteins: collagen, fibrin, elastin 2. Polysaccharides: alginate, chitosan, glycosaminoglycans, cellulose 3. De-cellularized scaffolds 4. Lipids Advantages of natural biomaterials - ANSWERbiofunctionality, biodegradable, less inflammation Disadvantages of natural biomaterials - ANSWERMechanical properties, stability, processing, immunogenicity (provoke immune res...