Hallmarks of cancer - Study guides, Class notes & Summaries

A summary of the lectures of signal transduction and hallmarks of cancer with additional questions and a recap after each lecture. Part of Bio-Pharmaceutical Sciences Master program - year 2022/2023 Lecture 1 - “Deregulating cellular energetics” Lecture 2- Hallmarks of Cancer Lecture 3 - Tumor Angiogenesis Lecture 4 - Activating invasion and metastasis Lecture 5 - How to develop a successful anticancer drug Lecture 6 - “Avoiding immune destruction and tumor promoting inflammati...

Oncogene - ANSWER-A gene that causes or contributes to the development of cancer Hallmarks of Cancer - ANSWER-Sustaining proliferative signaling Evading growth suppressors Activating invasion and metastasis Enabling replicative immortality Inducing angiogenesis Resisting cell death In vivo oncogenic evidence - ANSWER-Cause cancer when activated in a transgenic animal Render nontumorigenic cells tumorigenic Knock down or knock out in tumorigenic cells renders the cells nontumorigenic...

Oncogene - ANSWER-A gene that causes or contributes to the development of cancer Hallmarks of Cancer - ANSWER-Sustaining proliferative signaling Evading growth suppressors Activating invasion and metastasis Enabling replicative immortality Inducing angiogenesis Resisting cell death In vivo oncogenic evidence - ANSWER-Cause cancer when activated in a transgenic animal Render nontumorigenic cells tumorigenic Knock down or knock out in tumorigenic cells renders the cells nontumorigenic...

Ras signaling - GTPase - promotes growth and proliferation - mutated in 20-30% of all cancers - point mutations are most common G12V mutation - blocks GAP binding - locks RAS in active state, promoting proliferation Q61K mutation - raises activation energy of GTP hydrolysis - blocking hydrolysis, keeping RAS active Hallmarks of cancer 1) self-sufficiency in growth signals 2) insensitivity to anti-growth signals 3) unstable DNA 4) metastasis 5) evasion of apoptos...

CANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & AM Q & A

Cancer Cell Proliferation, Hallmarks of Cancer II, Hallmarks of Cancer III, Molecular Technology Qs&As Cancer - ANS-Uncontrolled cell growth and division Quiescence - ANS-Cell in a non-dividing state Senescence - ANS-Permanent cell cycle arrest Tissue homeostasis - ANS-Maintenance of a stable cell population in a tissue Carcinogenesis - ANS-Process of cancer development Initiators - ANS-Agents that cause DNA damage and initiate cancer Promoters - ANS-Agents that promote the growth of i...

Cancer Cell Proliferation, Hallmarks of Cancer II, Hallmarks of Cancer III, Molecular Technology Qs&As Cancer - ANS-Uncontrolled cell growth and division Quiescence - ANS-Cell in a non-dividing state Senescence - ANS-Permanent cell cycle arrest Tissue homeostasis - ANS-Maintenance of a stable cell population in a tissue Carcinogenesis - ANS-Process of cancer development Initiators - ANS-Agents that cause DNA damage and initiate cancer Promoters - ANS-Agents that promote the growth of i...

CANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTCANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & AURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & A

CPPS 325 - Cancer Part 2 Hallmarks of Cancer Exam @ 2023...

CANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & ACANCER BIOLOGY LECTURE 3 CELLULAR HALLMARKS OF CANCER REVIEW EXAM Q & A