Nurs 2514 drugs - Study guides, Class notes & Summaries

Nurs 2514 – Drugs Questions with Correct Answers

Methotrexate* Correct Answer-Antimetabolite (Antifolate), S-phase USE oncology, non-hodgkins, head and neck sarcomas, choriocarcinoma MOA inhibition of folic acid synthesis, disrupts synthesis of DNA precursors, induces programmed cell death ROUTE po/Im/iv/it ONSET/PEAK 4-7d/7-14d ELIMINATION urine S/E interstitial pneumonitis, renal failure, myelosuppression, thrombocytopenia, anemia, hemorrhage, septicemia, hepatic toxicity INTERACTIONS MONITOR CBC, neurological, hepatic, renal, lung ...