Pcol 824 drugs - Study guides, Class notes & Summaries

PCOL 824 DRUGS Exam Questions and Answers All Correct ACE inhibitors suffix - Answer--pril ACE inhibitor that has a Short Half Life - Answer-Captopril ACE inhibitors MOA - Answer-Inhibit ACE--> decrease angiotensin II--> decrease GFR (prevent constriction of efferent arteriole) Increasing levels of renin (loss of feedback) ACE inhibition--> prevents inactivation of bradykinin (vasodilator) Bradykinn increase, Cough ACE-2 does it degrade angiotensin II - Answer-ACE-2 de...

PCOL 824 Exam 1 Questions with Correct Answers The comparison of LSD to Alcohol to Klonopin to Etorphine shows - Answer-there are very large differences in the amount of drugs needed to produce a pharmacologic effect. even if the effects are similar some drugs like LSD seem to be ____ while others like alcohol are ___ - Answer-Selective not selective chemically closely related drugs like morphine and etoprhine probably share _____ but ___ - Answer-similar mechanism of actions th...

PCOL 824 Final Exam Questions with Answers All Correct serotonin receptor (5HT2C) - Answer-serotonin binding activates the satiety pathway leptin - Answer--hormone produced in fat cells -stimulates the satiety pathway and inhibits the hunger pathway ghrelin - Answer-stimulates the NPY pathway (hunger) amphetamine-like drugs - Answer--short term management of obesity (appetite suppressant) ADR: weight rebound orlistat - Answer-irreversible inhibitor of GI lipase (decreases fat a...

PCOL 824 Exam 2 Questions with Correct Answers What is the equation for Vd? - Answer-Vd = initial dose of drug in body / concentration of drug in plasma High Vd - Answer-Drug is mostly found in tissues - not affected by changes to protein binding - favored being present in the cells Low Vd - Answer-Drug is mostly in blood - very protein bound (albumin) - sensitive to changes in protein binding Order of Lowest to Highest Vd - Answer-Drug that highly binds to proteins and cannot enter t...

PCOL 824 Exam 1 2024 Questions with 100% Correct Answers Verified A+