Phpr 813 Study guides, Class notes & Summaries

PHPR 813 EXAM 1 QUESTIONS WITH COMPLETE SOLUTIONS!!

PHPR 813 Study Questions with 100% Correct Verified Answers Is Mycobacterium gram positive or negative? gram positive (purple) Tell me something about Mycobacterium's cell wall it has a high lipid content (wax-like appearance) - mycolic acids - lipoarabinomannan Acid fast stain is used to differentiate this bacteria

Fungi - -Eukaryotes -have: nucleus, mitochondria, and endoplasmic reticulum -Differ from mammalian cells by: rigid cell wall, cell wall sterol is ergosterol rather than cholesterol Polymers that give the cell wall rigidity - Glucan and Chitin Fungal Cells: Chitin and Glucans: - -Responsible for rigidity - both are potential targets for antifungal drugs

What are bacterial nucleic acids DNA (forms a nucleoid) and Plasmids How many base pairs in bacterial DNA several million Roughly how many base pairs in plasmids ~20,000 What are the subunits in prokaryotic ribosomes 50S and 30S = 70S sedimentation Which ribosomal subunit can help identify a specific microbe 30S subunit

Bacteria Structure Capsule, outer membrane (only in gram-negative bacteria), cell wall murein, cytoplasmic membrane, nucleus equivalent, plasmid, 70S ribosomes, depot substances (metaphosphates, glycogen), flagella, attachment pili Gram-Positive Bacteria Thick peptidoglycan membrane (cross-links between NAM + peptide and NAG)

Major Groups of Microorganisms - Bacteria (prokaryote) - Fungi (eukaryote) - Viruses - Protozoa (eukaryote) - Algae Major Groups of Microorganisms: Bacteria (prokaryote) Commensal bacteria Opportunistic bacteria Pathogenic bacteria

Do gram + or - cells have an outer-membrane? gram negative What component of a bacterial cell is made of peptidoglycan? cell wall Describe the order of membranes in bacterial cells? Capsule (all cells) Outer membrane (gram - only) Cell wall (peptidoglycan) Cytoplasmic membrane

What are the different types of bacteria? - Commensal, opportunistic, pathogenic Bacteria are prokaryotes (have nucleus) What are the different kinds of fungi? - Yeast and mold Fungi are eukaryotes What are the different kinds of Protozoa? - Free-living and parasitic

Malaria - Caused by Anopheles Sp. / Plasmodium spp. 250 million annual cases - 1 million deaths 1 in 5 childhood deaths in africa pregnant women are high risk of dying cannot donate blood for 3 months after travel, 3 years after living there parasitic infection Plasmodium falciparum - malaria short incubation severe malaria cases majority of US malaria cases