Prescribing sbom Study guides, Class notes & Summaries
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Prescribing SBOM Questions & Answers Already Graded A+
- Exam (elaborations) • 13 pages • 2024
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acute testing - usually single dose study 
causes of confusion in the elderly - - sepsis 
- 'something in the head'- tumour, CVA, subdural, meningitis 
- medication 
- metabolic: dec Na, dec glucose, AKI 
chronic testing - Repeated doses for 1-2 yrs; used to investigate carcinogenicity 
clinical trials: phase 1 - Define route & metabolic fate in normal volunteers (n<50). 
Initial dose: usually 1/20th or 1/50th of effective dose in animals. 
ADR monitored by clinical biochemistry etc 
clinic...
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