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Test Bank For Lippincott Illustrated Reviews: Pharmacology 7th Edition by Karen Whalen | 9781496384133 | Chapter 1-48 |All Chapters with Answers and RationalsR306,64
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Test Bank For Lippincott Illustrated Reviews: Pharmacology 7th Edition by Karen Whalen | 9781496384133 | Chapter 1-48 |All Chapters with Answers and Rationals
Title: Lippincott Pharmacology Illustrated Reviews 7th Edition Whalen Test Bank
ISBN: 9781496384133
Number of Pages: 509
Edition: 7th
Author: Whalen
Number of Chapters: 48
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FULL TEST BANK
lippincott Pharmacology Illustrated
Reviews 7th Edition
Complete Test bank, All Chapters are included. Table of content
1: Pharmacokinetics 2: Drug–Receptor Interactions and Pharmacodynamics 3: The Autonomic Nervous System 4: Cholinergic Agonists 5: Cholinergic Antagonists 6: Adrenergic Agonists 7: Adrenergic Antagonists 8: Drugs for Neurodegenerative Diseases 9: Anxiolytic and Hypnotic Drugs 10: Antidepressants 11: Antipsychotic Drugs 12: Drugs for Epilepsy 13: Anesthetics 14: Opioids 15: Drugs of Abuse 16: CNS Stimulants 17: Antihypertensives 18: Diuretics 19: Heart Failure 20: Antiarrhythmics 21: Antianginal Drugs 22: Anticoagulants and Antiplatelet Agents 23: Drugs for Hyperlipidemia 24: Pituitary and Thyroid 25: Drugs for Diabetes 26: Estrogens and Androgens 27: Adrenal Hormones 28: Drugs for Obesity 29: Drugs for Disorders of the Respiratory System 30: Antihistamines 31: Gastrointestinal and Antiemetic Drugs 32: Drugs for Urologic Disorders 33: Drugs for Anemia 34: Drugs for Dermatologic Disorders 35: Drugs for Bone Disorders 36: Anti-inflammatory, Antipyretic, and Analgesic Agents 37: Principles of Antimicrobial Therapy 38: Cell Wall Inhibitors
39: Protein Synthesis Inhibitors 40: Quinolones, Folic Acid Antagonists, and Urinary Tract Antiseptics 41: Antimycobacterial Drugs 42: Antifungal Drugs 43: Antiprotozoal Drugs 44: Anthelmintic Drugs 45: Antiviral Drugs 46: Anticancer Drugs 47: Immunosuppressants 48: Clinical Toxicology Pharmacology Illustrated Reviews 7th Edition Whalen Test Bank Chapter 1: Pharmacokinetics MULTIPLE CHOICE 1. Which drugs will go through a pharmaceutic phase after it is administered?
a. Intramuscular cephalosporins
b. Intravenous vasopressors
c. Oral ana lgesics
d. Subcutaneous antiglycemics
ANS: C When drugs are administere d parenterally, there is no pharmaceutic phase, which occurs when a drug becomes a solution that can cross the biologic membrane. DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSING PROCESS : Assessment MSC : NCLE X: Physiological Integrity : Pharmacological an d Parenteral Therapies 2.The nurse is preparin g to administer an oral medication an d wants to ensure a rapi d drug
action. Which form of the medication will the nurse administer? a. Capsule
b. Enteric -coated pill
c. Liquid suspension
d. Tablet
ANS: C Liqui d drugs are already in solution, which is the form necessary for absorption in the GI tract. The other forms must disintegrate into small particles and then dissolve before being absorbed. DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSING PROCESS: Nursing Intervention MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies 3. The nurse is teaching a patient who wi ll be discharged home with a prescription for an enteric -
coated tablet. Which statement by the patient indicates understanding of the teaching? a. I may crush the tablet and put it in applesauce to improve absorption.
b. I should consume acidic foods to en hance absorption of this medication.
c. I should expect a delay in onset of the drugs effects after taking the tablet.
d. I should take this medication with high -fat foods to improve its action.
ANS: C Enteric-coate d tablets resist disintegration in the acidic environment of the stomach and disintegrate when they reach the small intestine. There is usually some delay in onset of actions after takin g these medications. Enteric-coated tablets shoul d not be crushe d or chewed, which woul d alter the time an d location of absorption. Acidic foods will not enhance the absorption of the medication. The patient shoul d not to eat high-fat food before ingestin g an enteric-coated tablet, because high-fat foods decrease the absorption rate. DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3
TOP: NURSING PROCESS : Nursin g Intervention MSC : NCLE X: Physiological Integrity : Pharmacological an d Parenteral Therapies 4.A patient who is newly diagnose d with type 1 diabetes mellitus asks why insuli n must be
given by subcutaneous injection instea d of by mouth. The nurse will explai n that this is because a. absorption is diminished by the first -pass effects in the liver.
b. absorption is faster when insulin is given subcutaneously.
c. digestive enzymes in the gastrointestinal tr act prevent absorption.
d. the oral form is less predictable with more adverse effects.
ANS: C Insulin, growth hormones, an d other protein-based drugs are destroye d in the small intestine by digestive enzymes an d must be given parenterally. Because insulin is destroye d by digestive enzymes, it woul d not make it to the liver for metabolism with a firs t-pass effect. Subcutaneous tissue has fewer bloo d vessels, so absorption is slower in such tissue. Insulin is given subcutaneously because it is desirable to have it absorb slowly. DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSING PROCESS : Nursin g Interventio n: Patient Teaching MSC : NCLE X: Physiological Integrity : Pharmacological an d Parenteral Therapies 5. The nurse is preparing to ad minister an oral medication that is water -soluble. The nurse
understands that this drug a. must be taken on an empty stomach.
b. requires active transport for absorption.
c. should be taken with fatty foods.
d. will readily diffuse into the gastrointestina l tract.
ANS: B Water-soluble drugs require a carrier enzyme or protein to pass through the GI membrane. DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 4 TOP: NURSING PROCESS : Nursin g Intervention MSC : NCLE X: Physiological Integrity : Pharmacological an d Parenteral Therapies 6. A nurse is preparin g to administer an oral dr ug that is best absorbe d in an acidic environment. How will the nurse give the drug? a. On an empty stomach
b. With a full glass of water
c. With food
d. With high -fat food
ANS: C Food can stimulate the production of gastric aci d so medications requiri ng an acidic environment should be given with a meal. High-fat foods are useful for drugs that are lipid soluble. DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 4 TOP: NURSING PROCESS : Nursin g Intervention MSC : NCLE X: Physiological Integrity : Pharmacological an d Parenteral Therapies 7. The nurse is preparin g an injectable dr ug an d wants to administer it for rapi d absorption. How will the nurse give this medication? a. IM i nto the deltoid muscle
b. IM into the gluteal muscle
c. SubQ into abdominal tissue
d. SubQ into the upper arm
ANS: A Drugs given IM are absorbe d faster in muscles that have more bloo d vessels, such as the deltoid, rather than those with fewer bloo d vessels, such as the gluteals. Subcutaneous routes are used when absorption needs to be slower and more sustained. DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 4 TOP: NURSING PROCESS : Planning MSC : NCLE X: Physiological Integrity : Pharmacological an d Parenteral Therapies 8. The nurse is reviewi ng medication information with a nursi ng student prior to administering an oral dr ug an d notes tha t the dr ug has extensive first-pass effects. Which statement by the student indicates a nee d for further teachin g abo ut this medication? a. The first-pass effect means the dr ug may be absorbe d into systemic circulation from the intestinal lumen. b. The first -pass effect means the drug may be changed to an inactive form and excreted.
c. The first -pass effect means the dru g may be changed to a metabolite, which may be more
active than the original. d. The first-pass effect means the dr ug may be unchange d as it passes through the liver.
ANS: A Drugs tha t under go first-pass metabolism are absorbe d into the portal vein from the intestinal lumen an d go through the liver where they are either unchange d or are metabolize d to an inactive or a more active form. DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 4 TOP: NURSING PROCESS : Nursin g Intervention MSC : NCLE X: Physiological Integrity : Pharmacological an d Parenteral Therapies 9. The nurse prepares to change a patients medication from an intravenous to an oral form and notes tha t the oral form is ordere d in a higher dose. The nurse understands that this is due to differences in a. bioavailability.
b. pinocytosis.
c. protein binding.
d. tachyphylaxis.
ANS: A Oral drugs may have less bioavailability because a lower percentage of the dr ug reaches the systemic circulation. Pinocytosis refers to the process by which cells carry a solute across a membrane. Protein bindi ng can occur with both routes. Tachyphylaxis describes a rapi d decrease in response to drugs that occurs when tolerance develops quickly. DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 4 TOP: NURSING PROCESS : Assessment MSC : NCLE X: Physiological Integrity : Pharmacological an d Parenteral Therapies 10. The nurse is preparin g to administer a dr ug an d learns that it binds t o protein at a rate of 90%. The patients serum albumin level is low. The nurse will observe the patient for a. decreased drug absorption.
b. decreased drug interactions.
c. decreased drug toxicity.
d. increased drug effects.
ANS: D Drugs tha t are highly protein-boun d bind with albumin an d other proteins, leavi ng less free drug in circulation. If a patient has a lo w albumin, the dr ug is no t bound, an d there is more free drug to cause dr ug effects. There woul d be increase d absorption, increase d interactions with other drugs, and increased toxicity. DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 5 TOP: NURSING PROCESS : Evaluation MSC : NCLE X: Physiological Integrity : Pharmacological an d Parenteral Therapies 11. The nurse is administerin g two drugs to a patient an d learns that both drugs are highly protein-bound. The nurse may expect a. decreased bioavailability of both drugs.
b. decreased drug effects.
c. decreased drug interactions.
d. increased risk of adverse effects.
ANS: D Two drugs that are highly protein -bound will compete for protein -binding sites, leaving more free dr ug in circulation an d an increase d risk of adverse effects as well as increased bioavailability, increased drug effects, and increased drug interactions. DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 5 TOP: NURSING PROCESS : Evaluation MSC : NCLE X: Physiological Integrity : Pharmacological an d Parenteral Therapies 12. A patient has been takin g a dr ug that has a protein-bindin g effect of 75%. The provider adds a new medication that has a protein-bindi ng effect of 90%. The nurse will expect a. decreased drug effects of the first drug.
b. decreased therapeutic range of the first drug.
c. increased drug effects of the first drug.
d. increased therapeutic range of the first drug.
ANS: C Addi ng another highly protein-boun d drug will displace the first dr ug from protein-bindi ng sites and release more free dr ug increasi ng the drugs effects. This does not alter the therapeutic range, which is the serum level between drug effectiveness and toxicity. DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 5 TOP: NURSING PROCESS : Nursin g Intervention/Evaluation MSC : NCLE X: Physiological Integrity : Pharmacological an d Parenteral Therapies 13. The nurse gives a medication to a patient with a history of liver disease. The nurse will monitor this patient for a. decreased drug effects.
b. increased drug effects.
c. decreased therapeutic range.
d. increased therapeutic range.
ANS: B Liver diseases such as cirrhosis and hepatitis alter drug metabolism by inhibiting the drug -
metabolizing enzymes in the liver. When the drug metaboli sm rate is decreased, excess drug accumulation can occur and lead to toxicity. DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 6 TOP: NURSING PROCESS : Assessment/Nursin g Intervention MSC : NCLE X: Physiological Integrity : Pharmacological an d Parenteral Therapies 14. The nurse gives 800 m g of a dr ug tha t has a half-life of 8 hours. Ho w much dr ug will be left in the body in 24 hours if no additional dr ug is given? a. None
b. 50 mg
c. 100 mg
d. 200 mg
ANS: C Eight hours after the dr ug is given, there will be 400 m g left. Eight hours after tha t (16 hours), there will be 200 mg left. At 24 hours, there will be 100 mg left. DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 6 TOP: NURSING PROCESS : Evaluation MSC : NCLE X: Physiological Integrity : Pharmacological an d Parenteral Therapies 15. If a dr ug has a half-life of 12 hours an d is given twice daily startin g at 0800 on a Monday, when will a steady state be achieved? a. 0800 on Tuesday
b. 0800 on Wednesday
c. 0800 on Thursday
d. 0800 on Friday
ANS: B Stead y-state levels occur at 3 to 5 half -lives. Wednesday at 0800 is 4 half -lives from the original dose. DIF: COGNITIVE LEVEL: Applying (Application) REF: Pages 6 -7 TOP: NURSING PROCESS: Evaluation MSC: NCLEX: Physiological Integrity: Pharmacological and Paren teral Therapies 16. The nurse is preparing to administer a drug that is ordered to be given twice daily. The nurse
reviews the medication information and learns that the drug has a half -life of 24 hours. What will the nurse do next? a. Administer the medic ation as ordered.
b. Contact the provider to discuss daily dosing.
c. Discuss every -other -day dosing with the provider.
d. Hold the medication and notify the provider.
ANS: B A drug with a longer half-life should be given at longer intervals to avoid drug toxicity. DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 12 TOP: NURSING PROCESS : Planning MSC : NCLE X: Physiological Integrity : Pharmacological an d Parenteral Therapies 17. The nurse is cari ng for a patient who has taken an overdose of aspirin several hours prior. The provider orders sodium bicarbonate to be given. The nurse understands that this dr ug is given for which purpose? a. To counter the toxic effects of the aspirin
b. To decrease the half -life of the aspirin
c. To increase the excretion of the aspirin
d. To neutralize the acid of the aspirin
ANS: C Aspirin is a wea k aci d and is more readily excrete d in alkaline urine. Sodium bicarbonate alkalizes the urine. It does n ot act as an antidote to aspirin, decrease the half-life, or neutralize its pH. DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 7 TOP: NURSING PROCESS : Planning MSC : NCLE X: Physiological Integrity : Pharmacological an d Parenteral Therapies 18. The nurse is preparin g to administer a dr ug tha t is eliminate d through the kidneys. The nurse reviews the patients chart an d notes tha t the patient has increase d serum creatinine an d blood urea nitrogen (BUN). The nurse will perform which action? a. Administer the drug as ordered.
b. Anticipate a shorter than usual half -life of the dru g.
c. Expect decreased drug effects when the drug is given.
d. Notify the provider and discuss giving a lower dose.
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