TEST BANK
Fundamentals of Biochemistry
Donald Voet, Stephen Woski, Judith G. Voet, Charlotte W. Pratt, and Destin Heilman 6th Edition Table of Contents
Chapter 01 Introduction to the Chemistry of Life 1
Chapter 02 Water 21
Chapter 03 Amino Acids and Polypeptides 43
Chapter 04 Proteins: Three-Dimensional Structure 71
Chapter 05 Carbohydrates 94
Chapter 06 Nucleotides, Nucleic Acids, and Genetic Information 122
Chapter 07 Lipids and Biological Membranes 143
Chapter 08 Membrane Transport 168
Chapter 09 Enzymatic Catalysis 186
Chapter 10 Enzyme Kinetics, Inhibition and Control 205
Chapter 11 Biochemical Signaling 228
Chapter 12 Introduction to Metabolism 258
Chapter 13 Glucose Metabolism 286
Chapter 14 Glycogen Metabolism 322
Chapter 15 Citric Acid Cycle 346
Chapter 16 Electron Transport and Oxidative Phosphorylation 373
Chapter 17 Photosynthesis 400
Chapter 18 Lipid Metabolism 430
Chapter 19 Amino Acid Metabolism 458
Chapter 20 Mammalian Fuel Metabolism: Integration and Regulation 487
Chapter 21 Nucleotide Metabolism 518
Chapter 22 DNA Replication 546
Chapter 23 Repair and Recombination 565
Chapter 24 Transcription and RNA Processing 576
Chapter 25 Protein Synthesis 602
Chapter 26 Regulation of Gene Expression 627 Chapter 1: Introduction to the Chemistry of Life Matching Choose the correct answer from the list. Not all th e answers will be used. A) phylogenetic B) negative C) H2O D) H° E) H – TS F) halobacteria G) open H) entropy I) flux J) polymers K) G° L) thermophiles M) nitrogen N positive 1. The most abundant molecule in the human body is _____. Answer: C Difficulty: Easy Bloom’s: Remember Learning Objective: LO 1.1 Discuss the origins and evolution of biological molecules Section Reference: 1.1.A The Origin of Life 2. During chemical evolution, small organic molecu les condense to form more complex molecules called ______. Answer: J Difficulty: Easy Bloom’s: Remember Learning Objective: LO 1.1 Discuss the origins and evolution of biological molecules Section Reference: 1.1.B The Origin of Life ______________________________________________________________________________________________
______________________________________________________________________________________________Test Bank - Fundamentals of Biochemistry, 6th Edition (Voet, 2024)
1 | P a g e 3. Evolutionary relationships can be visualized us ing a ______ tree. Answer: A Difficulty: Easy Bloom’s: Remember Learning Objective: LO 1.2 Explain how important fe atures of cell architecture relate to the structure and function of cells Section Reference: 1.2.C Cellular Architecture 4. The organisms most likely to be found in a brin e environment would be ______. Answer: F Difficulty: Easy Bloom’s: Remember Learning Objective: LO 1.2 Explain how important fe atures of cell architecture relate to the structure and function of cells Section Reference: 1.2.C Cellular Architecture 5. The organisms most likely to be found in high t emperature environments would be ______. Ans: L Difficulty: Easy Bloom’s: Remember Learning Objective: LO 1.2 Explain how important fe atures of cell architecture relate to the structure and function of cells Section Reference: 1.2.C Cellular Architecture 6. The term used to indicate the degree of randomn ess within a system is ______. Ans: H Difficulty: Easy Bloom’s: Remember Learning Objective: LO 1.3 Distinguish the first a nd second laws of thermodynamics Section Reference: 1.3.B Thermodynamics ______________________________________________________________________________________________
______________________________________________________________________________________________Test Bank - Fundamentals of Biochemistry, 6th Edition (Voet, 2024)
2 | P a g e 7. Spontaneous processes are characterized by a cha nge in Gibbs free energy that is ______. Ans: B Difficulty: Easy Bloom’s: Understand Learning Objective: LO 1.3 Distinguish the first a nd second laws of thermodynamics Section Reference: 1.3.B Thermodynamics 8. Gibbs free energy is defined as G = ______. Ans: E Difficulty: Easy Bloom’s: Remember Learning Objective: LO 1.3 Distinguish the first an d second laws of thermodynamics Section Reference: 1.3C Thermodynamics 9. The symbol for free energy under standard bioch emical conditions is ______. Ans: K Difficulty: Easy Bloom’s: Remember Learning Objective: LO 1.3 Distinguish the first an d second laws of thermodynamics Section Reference: 1.3.B Thermodynamics 10. Living creatures can be described thermodynami cally as ______ systems. Ans: G Difficulty: Easy Bloom’s: Remember Learning Objective: LO 1.3 Distinguish the first an d second laws of thermodynamics Section Reference: 1.3.E Thermodynamics ______________________________________________________________________________________________
______________________________________________________________________________________________Test Bank - Fundamentals of Biochemistry, 6th Edition (Voet, 2024)
3 | P a g e Multiple Choice 11. What are the four most abundant elements in a human body? A) C, N, O, H B) C, N, O, P C) C, S, O, H D) C, Na, O, H Answer: A Difficulty: Moderate Bloom’s: Analyze Learning Objective: LO 1.1 Discuss the origins and evolution of biological molecules Section Reference: 1.1.A The Origin of Life 12. The atmosphere of prebiotic earth probably con tained the following molecules: A) H 2O, CO 2, N2 , CH 4, and NH 3. B) H 2O, CO 2, CH 4, C6H12O6, and NH 3. C) H 2O, CO 2, CH 4, C6H12O6, and COO-CH 2NH+3. D) H 2O, CO 2, CH 4, COOHCH 2NH 3, and NH 3. Answer: A Difficulty: Easy Bloom’s: Remember Learning Objective: LO 1.1 Discuss the origins and evolution of biological molecules Section Reference: 1.1.A The Origin of Life 13. In 1953, Urey and Miller carried out an experi ment in which they subjected a mixture of H2O, CH 4, NH 3, and H 2 to electrical discharges. Which of the following were among the products? A) proteins B) amino acids C) nucleic acids D) ribosomes Answer: B Difficulty: Easy ______________________________________________________________________________________________
______________________________________________________________________________________________Test Bank - Fundamentals of Biochemistry, 6th Edition (Voet, 2024)
4 | P a g e Bloom’s: Remember Learning Objective: LO 1.1 Discuss the origins and evolution of biological molecules Section Reference: 1.1.A The Origin of Life 14. Which of the following statements about hydrot hermal vents is true? A) The vents have temperatures as high as 1000oC and emit H2S and metal sulfides. B) The vents have temperatures as high as 800°C an d emit H 2S and metal sulfides. C) The vents have temperatures as high as 600°C an d emit H 2S and metal nitrates. D) The vents have temperatures as high as 400°C an d emit H 2S and metal sulfides. Answer: D Difficulty: Moderate Bloom’s: Apply Learning Objective: LO 1.1 Discuss the origins and evolution of biological molecules Section Reference: 1.1.A The Origin of Life For questions 15-18, consider the structure of the coenzyme NADP. 15. Which arrow points at a phosphate ester bond? A) A B) B N
NNNNH2
O
OOHHH
H HO
P
OO OPO
O OPO
O
O
OHOHHH
H HO NNH2O
C
D
EB
A______________________________________________________________________________________________
______________________________________________________________________________________________Test Bank - Fundamentals of Biochemistry, 6th Edition (Voet, 2024)
5 | P a g e C) D D) E Answer: D Difficulty: Easy Bloom’s: Remember Learning Objective: LO 1.1 Discuss the origins and evolution of biological molecules Section Reference: 1.1.A The Origin of Life 16. Which arrow points at an amide bond? A) B B) C C) D D) E Answer: B A Difficulty: Easy Bloom’s: Remember Learning Objective: LO 1.1 Discuss the origins and evolution of biological molecules Section Reference: 1.1.A The Origin of Life 17. Which arrow points at an anhydride bond? A) A B) B C) D D) E Answer: A Difficulty: Moderate Bloom’s: Apply Learning Objective: LO 1.1 Discuss the origins and evolution of biological molecules Section Reference: 1.1.A The Origin of Life 18. Which of the following developed during the ev olution of eukaryotic cells from prokaryotic cells? A) DNA B) the cell membrane C) nuclear membranes D) ribosomes ______________________________________________________________________________________________
______________________________________________________________________________________________Test Bank - Fundamentals of Biochemistry, 6th Edition (Voet, 2024)
6 | P a g e Answer: C Difficulty: Easy Bloom’s: Understand Learning Objective: LO 1.2 Explain how important f eatures of cellular architecture relate to the structure and function of cells Section Reference: 1.2.B Cellular Architecture 19. Using phylogeny, all living organisms can be d ivided into the following domains: A) bacteria, eukarya, and vertebrate B) archaea and eukarya C) bacteria, eukarya, and archaea D) eukarya and bacteria Answer: C Difficulty: Moderate Bloom’s: Analyze Learning Objective: LO 1.2 Explain how important f eatures of cellular architecture relate to the structure and function of cells Section Reference: 1.2.C Cellular Architecture 20. The theory of evolution includes which of the following principles? A) Evolution is not directed toward a specific goa l. B) Evolution is ongoing, and is constrained by its past. C) Evolution does not require variation among indi viduals for adaptation to occur. D) A and B Answer: D Difficulty: Easy Bloom’s: Understand Learning Objective: LO 1.2 Explain how important f eatures of cellular architecture relate to the structure and function of cells Section Reference: 1.2.D Cellular Architecture 21. Which three cellular components are present in both prokaryotes and eukaryotes? A) ribosomes, chloroplasts, mitochondria B) nucleus, ribosomes, RNA C) RNA, DNA, ribosomes D) mitochondria, DNA, RNA ______________________________________________________________________________________________
______________________________________________________________________________________________Test Bank - Fundamentals of Biochemistry, 6th Edition (Voet, 2024)
7 | P a g e Answer: C Difficulty: Easy Bloom’s: Remember Learning Objective: LO 1.2 Explain how important f eatures of cellular architecture relate to the structure and function of cells Section Reference: 1.2.B Cellular Architecture 22. The bulk of aerobic metabolism in eukaryotic c ells takes place in A) the endoplasmic reticulum B) the nucleus C) the mitochondria D) peroxisomes Answer: C Difficulty: Easy Bloom’s: Remember Learning Objective: LO 1.2 Explain how important f eatures of cellular architecture relate to the structure and function of cells Section Reference: 1.2.B Cellular Architecture 23. Which cellular compartment or organelle is inv olved in the synthesis of cellular components such as proteins and lipids? A) endoplasmic reticulum B) lysosomes C) peroxisomes D) vacuoles Answer: A Difficulty: Moderate Bloom’s: Apply Learning Objective: LO 1.2 Explain how important f eatures of cellular architecture relate to the structure and function of cells Section Reference: 1.2.B Cellular Architecture 24. Which of the following is a similarity between all prokaryotes and all eukaryotes? A) Both contain DNA in a nucleus. B) Both contain some of the same membrane bound ce ll organelles (like mitochondria, Golgi complexes, etc.). ______________________________________________________________________________________________
______________________________________________________________________________________________Test Bank - Fundamentals of Biochemistry, 6th Edition (Voet, 2024)
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