Edition by Jacqueline Burchum- Laura Rosenthal |Complete
Guide A+
Pharmacokinetics - ANSWER: The affect the body has on drugs. The movement of drugs through the
body.
Pharmacodynamics - ANSWER: The affect drugs have on the body. The study of the biochemical and
physiologic effects of drugs and the molecular mechanisms by which those effects are produced.
Drug - ANSWER: Any chemical that can affect living processes.
Pharmacology - ANSWER: The study of drugs and their interactions with living systems.
Clinical Pharmacology - ANSWER: The study of drugs in humans.
Therapeutics(pharmacotherapeutics) - ANSWER: The use of drugs to diagnose, prevents, or treat
disease or to prevent pregnancy.
3 main properties of an ideal drug - ANSWER: Effectiveness, safety, selectivity
Effectiveness - ANSWER: a drug that elicits the responses it was designed for.
Safety - ANSWER: a drug that cannot produce harmful effects
Selectivity - ANSWER: a drug that elicits only the response for which it is given.
Additional Properties of an ideal drug - ANSWER: Reversible action, predictability, ease of
administration, freedom from drug interaction, low cost, chemical stability, possession of a simple
generic name
The Therapeutic Objective - ANSWER: To provide maximum benefit with minimal harm
Pre administration Assessment includes.. - ANSWER: collecting baseline data, identifying high-risk
patients, assessing the patient's capacity for self-care.
5 Rights of drug administration - ANSWER: Right drug, Right patient, Right route, Right dose, Right
time.
Additional rights of drug administration - ANSWER: Right assessment, Right documentation, Right
evaluation, Right patient education, Patient's right to refuse.
Evaluating Therapeutic Responses - ANSWER: evaluation of the patient before, during, and after
treatment to ensure that treatment is or isn't working. Also monitoring for toxicity/adverse effects
Promoting Patient Adherence - ANSWER: Ensuring the patient is properly educated about treatment,
monitoring their ability for self-care, ensuring they have access to necessary aspects of treatment.
Implementing Non-drug measures - ANSWER: Encouraging and educating patients on treatment
options other than drug therapy. Exercise, diet, PT, chiropractic, etc.
, Minimizing Adverse Effects requires the nurse to know... - ANSWER: The major adverse effects
possible of a drug, when these reactions are likely to occur, early signs that and adverse effect is
developing, interventions that can minimize discomfort and harm.
Minimizing Adverse Interactions requires.. - ANSWER: taking a thorough drug history(including
supplements, herbals, illegals, etc.), advising the patient to avoid OTCs, monitoring for adverse
interactions known to occur with these medications, and being alert for as-yet unknown interactions.
PRN decisions - ANSWER: A medication order in which the nurse has discretion regarding when to give
a drug and in some case, how much to give.
5 steps of the Nursing Process - ANSWER: 1) assessment 2) analysis 3) planning 4) implementation 5)
evaluation
Assessment includes.. - ANSWER: patient interview, medical and drug-use histories, physical
examination, observation of the patient, lab tests.
Analysis: Nursing Diagnoses includes.. - ANSWER: The analysis of the information gathered from the
assessment to determine actual and potential health problems. Physiological, psychological, or
sociological.
Planning includes.. - ANSWER: A plan to delineate specific interventions directed at solving or
preventing the problems identified in the analysis. Individual to the patient, define goals, set
priorities, identify nursing interventions, establish criteria for evaluating success.
Implementation - ANSWER: Carrying out the interventions identified during planning. Collaborative
interventions require assistance from a health care provider. Independent interventions do not. Also
involves coordinating actions of other members involved. Observing and documenting the outcomes
of treatment.
Evaluation - ANSWER: Determines the degree to which treatment was successful.
Federal Pure Food and Drug Act of 1906 - ANSWER: Set standards for drug quality and purity in
addition to strength. Focused on product labeling and required that variations from standards be
labeled.
Food, Drug, and Cosmetic Act of 1938 - ANSWER: Addressed drug safety. Congress requires all new
drugs undergo testing for safety. Results to be evaluated by the FDA and only those deemed "safe"
would receive approval.
Harris-Kefauver Amendments of 1962 - ANSWER: Sought to strengthen all aspects of drug regulation.
Drugs must be proved effective before marketing. And all drugs released between 1932 and 1962
must undergo testing for effectiveness. Also established rigorous testing for new drugs.
Controlled Substances Act of 1970 - ANSWER: It set rules for the manufacture and distribution of
drugs considered to have the potential for abuse.
5 categories of controlled substances - ANSWER: Schedules I, II, III, IV, V. Schedule I have no accepted
medical use in the US and are deemed to have a high potential for abuse. Schedule V is the lease
addictive.
Prescription Drug User Fee Act (PDUFA) of 1992 - ANSWER: Companies can pay a fee to accelerate
FDA approval of new drugs and hold the FDA to a strict review time schedule.
Stages of New Drug Development - ANSWER: Preclinical Testing, Clinical Testing (Phase I-IV)