3 Types of Adaptive Immunity correct answers -Active (natural=response to infection ;
artificial=response to vaccination)
-Passive (natural=antibody transfer across placenta ; artificial=antibody injection to help fight
infection
-Adoptive (received from bone marrow transplants)
Immunogen correct answers Substance that induces an immune response (proteins most potent,
followed by polysaccharides)
Antigen correct answers Substance that combines with final products of immune response (think
ANTI-body GEN-erator)
Epitope correct answers Immunologically active region of antigen
Immunogenicity Factors correct answers -Molecule must be recognized as foreign
-Molecular size (most active immunogens have mass > 10,000 daltons)
-Chemical composition and heterogeneity (protein organization contribute to immunogenicity)
-Susceptibility to antigen processing & presentation (large molecules generally more
immunogenic because they're easily phagocytized ; polymers of D-amino acids can't be
processed)
-Immunogen dosage & route of administration (low or high dose can induce tolerance ;
immunogen administered IV goes to spleen, immunogen administered subcutaneously goes to
lymph nodes)
Adjuvant correct answers Substance that is mixed with an antigen to enhance the immune
response
Blood Cell Classification correct answers Based on expression of CD markers on cell surface
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