Drug Biology VCU Exam 1 Questions and Answers Latest 2025 Update(Complete test bank 100% correct)
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Course
Drug Biology VCU
Institution
Drug Biology VCU
Which anticholinesterase is used to help Alzheimer's disease?
a. neostigmine
b. physostigmine
c. pyridostigmine
d. all of the above - ️️physostigmine
T/F: acetylcholine binds at the neuromuscular junction. - ️️true
Which receptors bind acetylcholine?
a. muscarinic
b. nicotinic
c. b...
Drug Biology VCU Exam 1
Which anticholinesterase is used to help Alzheimer's disease?
a. neostigmine
b. physostigmine
c. pyridostigmine
d. all of the above - ✔️✔️physostigmine
T/F: acetylcholine binds at the neuromuscular junction. - ✔️✔️true
Which receptors bind acetylcholine?
a. muscarinic
b. nicotinic
c. both
d. none - ✔️✔️muscarinic and nicotinic
Which of the following is true about acetylcholine?
a. it has a 3ºN and is charged
b. it has a 3ºN and is not charged
c. it has a 4ºN and is charged
d. it has a 4ºN and is not charged - ✔️✔️it has a 4ºN and is charged
Does acetylcholine have CNS effects? (Does it cross the blood brain barrier?) -
✔️✔️no
What enzyme rapidly breaks down acetylcholine? - ✔️✔️acetylcholinesterase
How does the botulism toxin cause paralysis? - ✔️✔️breaks down SNAREs
What kind of environments grow Clostridium botulinum? - ✔️✔️anaerobic, low salt,
basic
What is onabotulinumtoxin A used for? - ✔️✔️treating movement disorders and
achalasia
True or false: nicotinic acetylcholine receptors are ligand-gated ion channels? -
✔️✔️true
What a nicotinic acetylcholine receptor is activated, ____ comes in and ________
occurs. - ✔️✔️Na+, depolarization
Nicotine has a _______ and (is/is not) charged. - ✔️✔️3ºN, is not
, Does nicotine have CNS effects? (Does it cross the blood brain barrier?) - ✔️✔️yes
Which of the following illnesses are part of the Smoker's Paradox?
a. ADHD
b. Chrohn's
c. Arthritis
d. Schitzophrenia - ✔️✔️schizophrenia
What type of receptor is the muscarinic acetylcholine receptor? - ✔️✔️g-protein
coupled receptor
Which is not a parasympathetic activation?
a. SLUDE
b. bronchial constriction
c. miosis
d. all of the above - ✔️✔️all of the above
Which of the following is an agonist for muscarinic receptors?
a. muscarine
b. epinephrine
c. norepinephrine
d. multiple - ✔️✔️muscarine
What happens when an agonist binds to a muscarinic receptor?
a. increased heart rate
b. bronchi release
c. SLUDE
d. all of the above - ✔️✔️SLUDE
Bethanechol is used postoperatively to relieve GI distension or urinary retention. It is
a.... - ✔️✔️parasympathomimetic
Bethanechol is contraindicated in patients with:
a. coronary insufficiency
b. intestinal obstruction
c. asthma
c. all of the above - ✔️✔️all of the above
Carbamylcholine and pilocarpine are both ____________ used in ___________
solutions to cause ____________. - ✔️✔️parasympathomimetics, ophthalmic, miosis
Pilocarpine has a ____ nitrogen. - ✔️✔️3º
3ºN are _______ and ______cross the blood brain barrier. - ✔️✔️not charged, do
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